Interplane bulk motion analysis and removal based on normalized cross-correlation in optical coherence tomography angiography

Interplane bulk motion analysis and removal based on normalized cross-correlation in optical coherence tomography angiography
复制标题

光学相干断层扫描血管造影中基于归一化互相关的面间整体运动分析和去除

DOI:
10.1002/jbio.202000046
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发表时间:
2020
影响因子:
2.8
通讯作者:
Shi Guohua
Shi Guohua
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Fan Jinyu;He Yi;Wang Pinghe;Liu Guangxing;Shi Guohua

文献摘要

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Bulk motion seriously degrades the image quality of optical coherence tomography angiography (OCTA). Conventional correction methods focus on in‐plane displacement, while the bulk motion component perpendicular to B‐scans also introduces noise. This work first presents an evaluation of this component using a specific scan protocol and an approximate expression derived from peak‐normalized cross‐correlation values, and then quantitatively assesses how interplane bulk motion noise reduce the sensitivity of cross‐sectional angiograms. Finally, we developed a repetitive bulk motion correction method based on the estimated displacements and redundant volume scans. The correction does not require registration and angiogram reconstruction of low flow sensitivity frames, and the results of in vivo mice skin OCTA imaging experiments show that the proposed method can effectively reduce bulk motion noise caused by cardiac and respiratory motion and occasional shaking, and improve OCTA image quality, which has practical significance for clinical OCTA diagnosis and analysis.