Prediction of failure of inpatient treatment of anorexia nervosa from early weight gain
Prediction of failure of inpatient treatment of anorexia nervosa from early weight gain
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DOI：
10.1080/10503300600702315
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发表时间：
2007-03-01
影响因子：
3.9
通讯作者：
Zeeck, Almut
中科院分区：
文献类型：
--
作者：
Hartmann, Armin;Wirth, Caroline;Zeeck, Almut
神经性厌食症很难治疗，在治疗过程的早期识别有失败风险的患者是很重要的。85个连续入院的住院患者（DSM IV）进行了治疗的综合方法，包括治疗合同。出院时的失败定义为BMI小于17.5 kg/m2或体重增加< 2 kg/m2。统计分析包括生长曲线分析、最佳比例回归方法和ROC曲线。20%的患者被评为“失败”。第3周和第4周的体重曲线参数预测结果的有效性为p = 0.84。30%的患者被归类为“有失败风险”，其中82.4%被正确识别。长期病程的已知预测因子不能预测出院时的结局。体重增加曲线的特征（治疗的前四周）允许识别相当大比例的有失败风险的患者。
Anorexia nervosa is difficult to treat. It is important to identify patients at risk for failure early in the treatment process. Eighty-five consecutively admitted inpatients (DSM IV) were treated with an integrative approach including a treatment contract. Failure at discharge was defined as leaving with a BMI of less than 17.5 kg/m(2) or gaining < 2 kg/m(2) in weight. Statistical analysis consisted of growth curve analysis, methods of regression with optimal scaling and ROC-curves. Twenty percent of patients were rated as 'failures'. Parameters of weight curves of week 3 and 4 predicted outcome at an effectiveness of p = 0.84. Thirty percent of the patients were classified as 'at-risk-of-failure' and 82.4% of these were identified correctly. Known predictors of the long term course did not predict outcome status at discharge. Characteristics of the weight gain curve (first four weeks of treatment) allowed identification of a substantial proportion of patients at risk for failure.