CORTICOFUGAL INPUT TO TASTE-RESPONSIVE UNITS IN THE PARABRACHIAL PONS
CORTICOFUGAL INPUT TO TASTE-RESPONSIVE UNITS IN THE PARABRACHIAL PONS
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DOI：
10.1016/0361-9230(92)90167-v
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发表时间：
1992-12-01
影响因子：
3.8
通讯作者：
MONROE, S
中科院分区：
文献类型：
--
作者：
DILORENZO, PM;MONROE, S
本文观察了接受味觉新皮层直接投射的脑桥臂旁核（PbN）内味觉反应单位的变化。用双极刺激电极对GN进行电刺激。在PbN中鉴定的62个味觉反应单位中的19个（31%）中观察到对GN刺激的时间锁定反应。其中，17个单位产生兴奋性反应后，GN刺激和2个单位表现出抑制的证据。没有证据表明PbN单位的逆向激活是明显的。这些结果是一致的描述的解剖预测从GN的PbN，并表明，在PbN的味觉反应的神经元的一部分接收直接的皮质输入。GN刺激后的PbN单位不能与那些不遵循其自发率或其响应曲线的PbN单位区分开来。这些结果表明，轴突从GN不选择目标内的PbN的特定响应特性的基础上。
Taste responses in units in the parabrachial nucleus of the pons (PbN) that receive direct projections from the gustatory neocortex (GN) were examined in the rat. Electrical stimulation was applied to the GN with bipolar stimulating electrodes. Time-locked responses to GN stimulation were observed in 19 of 62 (31 %) taste-responsive units identified in the PbN. Of these, 17 units produced excitatory responses following GN stimulation and 2 units showed evidence of inhibition. No evidence of antidromic activation of PbN units was apparent. These results are consistent with descriptions of the anatomical projections from the GN to the PbN and demonstrate that some portion of taste-responsive neural elements within the PbN receive direct cortical input. PbN units that followed GN stimulation could not be distinguished from those that did not follow either by their spontaneous rates or their response profiles. These results suggest that axons from the GN do not select targets within the PbN based on the particular response properties.