Dietary Inflammatory Index and metabolic syndrome in Mexican adult population
Dietary Inflammatory Index and metabolic syndrome in Mexican adult population
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DOI：
10.1093/ajcn/nqaa135
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发表时间：
2020-08-01
影响因子：
7.1
通讯作者：
Barrientos-Gutierrez, Tonatiuh
中科院分区：
文献类型：
--
作者：
Canto-Osorio, Francisco;Denova-Gutierrez, Edgar;Barrientos-Gutierrez, Tonatiuh
背景资料：证据表明，低度炎症的原因代谢syndrome，并建议饮食作为一个推动者的慢性inflammation.Objective：我们评估了炎症性饮食和代谢syndrome在墨西哥adults.Methods的发展之间的关联：共399名参与者的卫生工作者队列研究被列入本研究。随访13年。代谢综合征的定义是存在以下组分中的≥ 3个：男性腰围≥ 102 cm或女性腰围≥ 88 cm，收缩压≥ 130 mmHg或舒张压≥ 85 mmHg，HDL胆固醇≥ 100 mg/dL。为了评估饮食的炎症潜力，我们使用了饮食炎症指数（DII），该指数分为四分位数。为了评估代谢综合征的风险，我们使用考克斯比例风险模型估计HR和95%CI。结果：调整潜在混杂因素后，我们发现DII最高四分位数（Q）的参与者与代谢综合征的发病率呈正相关（HRQ 4vsQ 1 = 1.99; 95%CI：1.03，3.85; P趋势= 0.04）。当我们将代谢综合征按其组成成分划分时，我们发现DII最高四分位数的参与者与高甘油三酯血症相关（HRQ 4vsQ 1 = 2.28; 95% CI：1.13，4.57; P趋势= 0.01），高血压（HRQ 4vsQ 1 = 2.22; 95% CI：1.03，4.77; P趋势= 0.032）和腹部肥胖（HRQ 4vsQ 1 = 2.68; 95%CI：1.06，6.79; P-trend = 0.02）结论：高炎症饮食与代谢综合征、高血压、腹型肥胖和高血脂症相关。需要进一步的研究来证实炎症和饮食在代谢综合征发展中的作用;然而，减少与炎症有关的饮食成分是可取的。
Background: Evidence suggests low-grade inflammation as the cause of metabolic syndrome and suggests diet as a promoter of chronic inflammation.Objective: We evaluated the association between inflammatory diets and the development of metabolic syndrome in Mexican adults.Methods: A total of 399 participants of the Health Workers Cohort Study were included in this study. The follow-up period was 13 y. Metabolic syndrome definition was the presence of >= 3 of the following components: waist circumference >= 102 cm for males or >= 88 cm for females, blood pressure >= 130 mmHg for systolic or >= 85 mmHg for diastolic, HDL cholesterol = 100 mg/dL. To evaluate the inflammatory potential of the diet we used the Dietary Inflammatory Index (DII), which was divided into quartiles. To assess the risk of metabolic syndrome we estimated HRs and 95% CIs using Cox proportional hazards models.Results: After adjustment for potential confounders, we found a positive association between participants in the highest quartile (Q) of DII and the incidence of metabolic syndrome (HRQ4vsQ1 = 1.99; 95% CI: 1.03, 3.85; P-trend = 0.04) over a period of 13 y. When we divided the metabolic syndrome by its components, we found that participants in the highest quartile of DII were associated with hypertriglyceridemia (HRQ4vsQ1 = 2.28; 95% CI: 1.13, 4.57; P-trend = 0.01), hypertension (HRQ4vsQ1 = 2.22; 95% CI: 1.03, 4.77; P-trend = 0.032), and abdominal obesity (HRQ4vsQ1 = 2.68; 95% CI: 1.06, 6.79; P-trend = 0.02).Conclusions: A highly inflammatory diet is associated with metabolic syndrome, hypertension, abdominal obesity, and hypertriglyceridemia. Further studies are needed to corroborate the role of inflammation and diet in the development of metabolic syndrome; yet, a reduction in dietary components that have been linked to inflammation is desirable.