Collagens of Poriferan Origin.

Collagens of Poriferan Origin.
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DOI:
10.3390/md16030079
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发表时间:
2018-03-03
期刊:
影响因子:
5.4
通讯作者:
Jesionowski T
Jesionowski T
中科院分区:
医学2区
文献类型:
--
作者:
Ehrlich H;Wysokowski M;Żółtowska-Aksamitowska S;Petrenko I;Jesionowski T

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海绵来源的胶原蛋白的生物合成、结构多样性和功能性仍然是科学争议的范例和原因。这篇综述的雄心勃勃的目标是提供对多孔胶原蛋白的彻底和全面的报道,作为一个多方面的主题,其中包含有趣的假设和许多具有挑战性的开放问题。本文对海绵中胶原蛋白的结构多样性、化学和生物化学进行了分析和讨论。特别关注海绵、IV 型胶原相关蛋白、来自去海绵的纤维状胶原和来自玻璃海绵骨骼结构的胶原。该综述还重点关注海绵胶原蛋白在技术、材料科学和生物医学方面的应用前景和趋势。
The biosynthesis, structural diversity, and functionality of collagens of sponge origin are still paradigms and causes of scientific controversy. This review has the ambitious goal of providing thorough and comprehensive coverage of poriferan collagens as a multifaceted topic with intriguing hypotheses and numerous challenging open questions. The structural diversity, chemistry, and biochemistry of collagens in sponges are analyzed and discussed here. Special attention is paid to spongins, collagen IV-related proteins, fibrillar collagens from demosponges, and collagens from glass sponge skeletal structures. The review also focuses on prospects and trends in applications of sponge collagens for technology, materials science and biomedicine.
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发表时间: 1941-01-01
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