Global fiber reconstruction becomes practical
Global fiber reconstruction becomes practical
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DOI：
10.1016/j.neuroimage.2010.09.016
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发表时间：
2011-01-15
期刊：
影响因子：
5.7
通讯作者：
Kiselev, Valerij
中科院分区：
文献类型：
--
作者：
Reisert, Marco;Mader, Irina;Kiselev, Valerij
整体纤维重建的目的是在扩散敏感型磁共振成像的基础上，提供整个脑白质体积内纤维结构的一致视图。给出了这一原理的一种新实现。该方法利用高角分辨率扩散成像(HARDI)获得的数据，这是一种满足临床要求的测量方法。在全局重建方法中，计算时间对于广泛的实际应用是可以接受的，这是第一次。该方法不涉及规定重构纤维末端位置的任何边界条件。这有助于最大限度地减少必要的用户交互和对操作员的依赖。在物理模型上获得的结果表明重建质量很高。在几名志愿者身上已经获得了活体结果。该算法发现了包括边缘系统在内的许多突出的分束，这对之前发布的全球跟踪版本来说是有问题的。(C)2010 Elsevier Inc.保留所有权利。
Global fiber reconstruction aims at providing a consistent view of the fiber architecture in the whole volume of cerebral white matter on the basis of diffusion-sensitized magnetic resonance imaging. A new realization of this principle is presented. The method utilizes data acquired with high angular resolution diffusion imaging (HARDI), a measurement method that fulfills clinical requirements. For the first time among global reconstruction methods, the computation time is acceptable for a broad class of practical applications. The method does not involve any boundary conditions that prescribe the location of the ends of reconstructed fibers. This helps to minimize necessary user interaction and operator dependence. Results obtained in a physical phantom demonstrate a high reconstruction quality. In vivo results have been obtained in several volunteers. The algorithm found a number of prominent fascicles including those in the limbic system, which had been problematic for a previously published version of global tracking. (C) 2010 Elsevier Inc. All rights reserved.