The role of histocompatibility antigens (HLA) in infection.
The role of histocompatibility antigens (HLA) in infection.
复制标题
组织相容性抗原（HLA）在感染中的作用。
作者：
R. Kaslow;S. Shaw
我们试图用流行病学术语来描述和评估在不到十年的时间里所做的工作，以确定一个独特的遗传系统对感染的易感性和反应的影响。它对疾病易感性的影响程度才刚刚开始测量，我们对HLA与疾病关联的机制和功能方面的理解还处于起步阶段。我们希望从前面的回顾中可以清楚地看到，随着工作的进展，免疫遗传学家、流行病学家和生物统计学家都可以相互提供很多东西。
We have tried to describe and evaluate in epidemiologic terms what has been done in less than a decade to define the influence of a unique genetic system on susceptibility and response to infection. The extent of its influence on disease susceptibility has only begun to be measured, and our understanding of the mechanistic and functional aspects of HLA and disease association is in its infancy. We hope it is clear from the foregoing review that the immunogeneticist, the epidemiologist, and the biostatistician all have much to offer each other as the work progresses.