A direct and useful route to difluoroacylsilanes and difluoroacylstannanes and their potential for the generation of structurally diverse difluoroketones
A direct and useful route to difluoroacylsilanes and difluoroacylstannanes and their potential for the generation of structurally diverse difluoroketones
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DOI：
10.1016/s0040-4039(01)01220-5
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发表时间：
2001-09-03
影响因子：
1.8
通讯作者：
Percy, JM
中科院分区：
文献类型：
--
作者：
Garayt, MR;Percy, JM
制备烯丙基三氟乙基醚2a-2d；每种都经过有效的脱氟化氢/金属化和捕获，得到一系列二氟烯醇硅烷和锡烷，它们可以轻松有效地重排为酰基金属。氟化物介导的酰基硅烷的苄基化和烯丙基化，以及乙烯基和酰基锡烷的Stille偶联均以中等至良好的产率实现。 (C) 2001 Elsevier Science Ltd. 保留所有权利。
Allyl trifluoroethyl ethers 2a-2d were prepared; each underwent efficient dehydrofluorination/metallation and trapping to afford a range of difluoroenol silanes and stannanes which rearranged easily and efficiently to the acyl metals. Fluoride-mediated benzylation and allylation of an acylsilane, and Stille coupling of the vinyl- and acyl-stannane were achieved in moderate to good yield. (C) 2001 Elsevier Science Ltd. All rights reserved.