Effect of Brown Rice, White Rice, and Brown Rice with Legumes on Blood Glucose and Insulin Responses in Overweight Asian Indians: A Randomized Controlled Trial
Effect of Brown Rice, White Rice, and Brown Rice with Legumes on Blood Glucose and Insulin Responses in Overweight Asian Indians: A Randomized Controlled Trial
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DOI：
10.1089/dia.2013.0259
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发表时间：
2014-05-01
影响因子：
5.4
通讯作者：
Krishnaswamy, Kamala
中科院分区：
文献类型：
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作者：
Mohan, Viswanathan;Spiegelman, Donna;Krishnaswamy, Kamala
背景资料：通过用糙米（BR）代替普通谷物主食白色大米（WR）来改善饮食中的碳水化合物质量，可能对降低糖尿病和相关并发症的风险产生有益影响。因此，我们的目的是比较BR，WR和BR与豆类（BRL）饮食对24小时血糖和胰岛素反应超重的亚洲Indians.Subjects和方法：15超重（身体质量指数，>= 23 kg/m2）亚洲印度人没有糖尿病谁是25 - 45岁参加了一项随机交叉研究。试验餐（非等热量，随意）是相同的，除了类型的大米和添加豆类（50克/天），并提供了连续5天。使用Medtronic MiniMed（Northridge，CA）iPro（TM）2连续葡萄糖监测装置评估葡萄糖曲线。相对于基线葡萄糖浓度的平均正变化计算为5天内每个试验日的每日增量曲线下面积（IAUC）并取平均值。空腹血清胰岛素测定之前和结束时，每个测试diet.Results：在5天的平均IAUC的百分比差异是19.8%，低于BR组比WR组（P = 0.004）。BRL进一步降低了血糖反应（与WR相比降低了22.9%（P = 0.02））。与WR组中观察到的5天百分比变化相比，BR组和BRL组的空腹胰岛素5天百分比变化分别低57%（P = 0.0001）和54%。BR和BRL dietes.Conclusions的血糖和胰岛素反应BR代替WR的消费可以帮助减少超重的亚洲印度人24小时血糖和空腹胰岛素反应。
Background: Improving the carbohydrate quality of the diet by replacing the common cereal staple white rice (WR) with brown rice (BR) could have beneficial effects on reducing the risk for diabetes and related complications. Hence we aimed to compare the effects of BR, WR, and BR with legumes (BRL) diets on 24-h glycemic and insulinemic responses among overweight Asian Indians.Subjects and Methods: Fifteen overweight (body mass index, >= 23 kg/m(2)) Asian Indians without diabetes who were 25-45 years old participated in a randomized crossover study. Test meals (nonisocaloric, ad libitum) were identical except for the type of rice and the addition of legumes (50 g/day) and were provided for 5 consecutive days. Glucose profiles were assessed using the Medtronic MiniMed (Northridge, CA) iPro (TM) 2 continuous glucose monitoring device. The mean positive change from baseline glucose concentration was calculated as the daily incremental area under the curve (IAUC) on each test day for 5 days and averaged. Fasting serum insulin was measured prior to and at the end of each test diet.Results: The percentage difference in 5-day average IAUC was 19.8% lower in the BR group than in the WR group (P=0.004). BRL further decreased the glycemic response (22.9% lower compared with WR (P=0.02). The 5-day percentage change in fasting insulin was 57% lower (P=0.0001) for the BR group and 54% lower for the BRL group compared with the 5-day percentage change observed in the WR group. The glycemic and insulinemic responses to the BR and BRL diets were not significantly different.Conclusions: Consumption of BR in place of WR can help reduce 24-h glucose and fasting insulin responses among overweight Asian Indians.