Precancerous changes in the cervix and risk of subsequent preterm birth

Precancerous changes in the cervix and risk of subsequent preterm birth
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DOI:
10.1111/j.1471-0528.2006.01107.x
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发表时间:
2007-01-01
影响因子:
5.8
通讯作者:
Quinn, M.
Quinn, M.
中科院分区:
医学1区
文献类型:
--
作者:
Bruinsma, F.;Lumley, J.;Quinn, M.

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目的:本研究的目的是:(1)检查接受宫颈癌前病变评估的妇女是否比一般人群有更高的早产率;(2)比较治疗妇女和未治疗妇女的早产率,调整可能的混杂因素。设计回溯性队列设计。设置教学医院。所有参考墨尔本皇家妇女医院(1982-2000)的妇女随后在维多利亚州围产期数据收集系统(n=5548)上记录分娩。方法记录医院不典型增生临床记录和基于人口的出生记录。主要结果指标
Objective The aims of this study were (i) to examine whether women referred for assessment of precancerous changes in the cervix had higher rates of preterm, birth compared with those in the general population and (ii) to compare preterm birth rates for treated and untreated women adjusting for possible confounding factors.Design Retrospective cohort design.Setting Teaching hospital.Population All women referred to the Royal Women's Hospital, Melbourne (1982-2000), who subsequently had a birth recorded on the Victorian Perinatal Data Collection system (n = 5548).Methods Record linkage of hospital dysplasia clinic records and population-based birth records.Main outcome measures Total preterm delivery (