Characteristics and correlation analysis of negative emotions, quality of life, and chinese medicine syndromes in patients with lung cancer after surgery: A cross-sectional study
Characteristics and correlation analysis of negative emotions, quality of life, and chinese medicine syndromes in patients with lung cancer after surgery: A cross-sectional study
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肺癌术后患者负性情绪、生活质量及中医证候特征及相关性分析：横断面研究
DOI：
10.4103/2311-8571.385512
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发表时间：
2023
影响因子：
4.4
通讯作者：
Ling Xu
中科院分区：
文献类型：
--
作者：
Cong;Yi;Sheng;Yi;Ao Qi;Ling;Jia;Jia;Wenying Yang;Qin Wang;Li;Xiong Qin;Ya;Ling Xu
目的：观察分析非小细胞肺癌(NSCLC)患者术后1~3个月的负性情绪和生活质量特征，总结其术后人群特点。材料和方法：巩固康复期为术后1~3个月。主要观察指标为一般医院焦虑和抑郁量表、欧洲癌症研究与治疗组织核心生活质量问卷(EORTC QLQ-C30)和EORTC QLQ-肺癌-13。次要观察指标为外周血细胞因子和免疫功能指标。采用单因素方差分析、Logistic回归等统计方法对这部分人群的特征进行分析。结果：在接受肺手术的患者中，巩固恢复期焦虑发生率为13.66%，抑郁发生率为10.38%。乏力、疼痛、呼吸困难、失眠、食欲不振评分明显高于其他症状(P=0.000)。焦虑的存在与手术部位有关(P<；0.05)，抑郁的存在与情绪功能和呼吸困难有关(P<；0.05)。结论：非小细胞肺癌患者术后负性情绪的发生与性别有关，负性情绪程度与生活质量呈负相关，与症状程度呈正相关。主要相关证候为肺经和经络。
Objective: The objective of the study was to observe and analyze the characteristics of negative emotions and quality of life (QoL) in patients with nonsmall cell lung cancer (NSCLC) from 1 to 3 months after surgery, and summarize their population characteristics after surgery. Materials and Methods: The consolidation rehabilitation period was defined as 1 to 3 months after surgery. The main observation indicators were the general Hospital Anxiety and Depression Scale, the European Organization for the Research and Treatment of Cancer Core QoL Questionnaire (EORTC QLQ-C30), and EORTC QLQ-Lung Cancer-13. The secondary observation indicators were peripheral blood cytokines and immune function indicators. Statistical methods such as one-way analysis of variance and logistic regression were used to analyze the characteristics of this part of the population. Results: Among patients who underwent lung surgery, the overall incidence of anxiety during consolidation recovery was 13.66%, and that of depression was 10.38%. The scores of fatigue, pain, dyspnea, insomnia, and loss of appetite were significantly higher than those of other symptoms (P = 0.000). The presence of anxiety was associated with the site of surgery (P < 0.05) and the presence of depression was associated with emotional functioning and dyspnea (P < 0.05). Conclusions: The occurrence of negative emotions in the postoperative NSCLC population is related to gender, and the degree of emotions is negatively correlated with QoL and positively correlated with the degree of symptoms. The main relevant syndromes are the pulmonary and meridian categories.
影响因子：
6.7
作者：
ZIGMOND, AS;SNAITH, RP
通讯作者：
SNAITH, RP