INCREASED INCIDENCE OF END-STAGE RENAL-FAILURE SECONDARY TO DIABETES-MELLITUS IN ASIAN ETHNIC-GROUPS IN THE UNITED-KINGDOM
INCREASED INCIDENCE OF END-STAGE RENAL-FAILURE SECONDARY TO DIABETES-MELLITUS IN ASIAN ETHNIC-GROUPS IN THE UNITED-KINGDOM
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DOI：
10.1111/j.1464-5491.1992.tb01860.x
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发表时间：
1992-08-01
影响因子：
3.5
通讯作者：
WALLS, J
中科院分区：
文献类型：
--
作者：
BURDEN, AC;MCNALLY, PG;WALLS, J
在英国，糖尿病肾病在亚裔患者中比在白色高加索人中更常见。本研究旨在确定这些种族人群中继发于糖尿病的终末期肾衰竭的发生率是否存在差异。使用1979年至1988年莱斯特郡继发于糖尿病的接受肾脏替代治疗的患者的风险发生率，估计了接受治疗的终末期肾衰竭的发生率。亚洲人种糖尿病患者估计人群的终末期肾衰竭发生率为486.6例（95% CI，185.1 - 788.1）/百万人-年/年，而白色高加索人为35.6例（17 - 54.2）。所有发生终末期肾衰竭的亚裔患者均患有非胰岛素依赖型糖尿病。在英国亚裔患者中继发于糖尿病的终末期肾衰竭的高发病率为资源规划和分配提供了重要的公共卫生意义，并需要启动改善该种族肾脏疾病的策略。
Diabetic renal disease is more common in patients of Asian ethnic origin than White Caucasians in the United Kingdom. This study determines whether a disparity in the incidence of end-stage renal failure secondary to diabetes mellitus exists between these ethnic groups. The incidence of treated end-stage renal failure was estimated using the person-time at risk incidence rate for patients receiving renal replacement therapy secondary to diabetes mellitus in the county of Leicestershire from 1979 to 1988. The incidence rate of end-stage renal failure expressed for the estimated population of patients with diabetes mellitus in patients of Asian ethnic origin was 486.6 (95 % CI, 185.1 to 788.1) cases per million person-years per year, compared to 35.6 (17 to 54.2) in White Caucasians. All patients of Asian ethnic origin developing end-stage renal failure had non-insulin-dependent diabetes. The high incidence of end-stage renal failure secondary to diabetes mellitus in patients of Asian ethnic origin in the UK imparts significant public health implications for resource planning and allocation, and the need to initiate strategies to ameliorate renal disease in this ethnic group.