Distribution of pressure gradients along hepatic vasculature
Distribution of pressure gradients along hepatic vasculature
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DOI：
10.1152/ajpheart.1997.272.6.h2826
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发表时间：
1997-06-01
影响因子：
4.8
通讯作者：
Rothe, CF
中科院分区：
文献类型：
--
作者：
MaassMoreno, R;Rothe, CF
为了验证肝窦压力与门静脉压力(P-PV)或腹腔静脉压(P-AVC)基本相同的假设，在α-氯醛糖-尿素麻醉兔肝表面附近的单个门静脉供应的肝血管网中测量了微血管压力。使用伺服零压测量系统，门静脉末端小静脉、肝窦和肝起始小静脉相对于右心房中部的压力分别为5.7±0.8(SD)、5.4±0.7和4.7±0.6毫米汞柱。平均P-PV为7.7+/-1.1 mm Hg，P-AVC为3.9+/-0.7 mm Hg。正弦压力(P-SINU)比P-PV平均低2.33±1.04 mm Hg，比P-AVC高1.54+/-0.63 mm Hg。正弦曲线上的压力梯度平均
To test the hypothesis that the hepatic sinusoidal pressure is virtually identical to the portal venous pressure (P-pv) or the abdominal vena caval pressure (P-avc), microvascular pressures were measured in liver vascular networks supplied by a single portal venule near the liver surface of alpha-chloralose-urethan-anesthetized rabbits. With the use of a servo-null pressure-measuring system, the pressures in terminal portal venules, sinusoids, and initial hepatic venules averaged 5.7 +/- 0.8 (SD), 5.4 +/- 0.7, and 4.7 +/- 0.6 mmHg, respectively, relative to the middle of the right atrium. The mean P-pv was 7.7 +/- 1.1 mmHg and the P-avc was 3.9 +/- 0.7 mmHg. The sinusoidal pressure (P-sinu) averaged 2.33 +/- 1.04 mmHg lower than the P-pv and 1.54 +/- 0.63 mmHg higher than the P-avc. The pressure gradient across the sinusoids averaged