ESTIMATION OF WRIGHTS FIXATION INDEX FROM GENOTYPIC FREQUENCIES
ESTIMATION OF WRIGHTS FIXATION INDEX FROM GENOTYPIC FREQUENCIES
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DOI：
10.1007/bf00958921
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发表时间：
1970-01-01
期刊：
影响因子：
1.5
通讯作者：
BROWN, AHD
中科院分区：
文献类型：
--
作者：
BROWN, AHD
对于估计基因型频率的群体，通常使用x2拟合优度统计量来检验估计值与Hardy-Weinberg定律预测值的偏差。Wright 'sF检验的极大似然估计及其方差是一个相似的检验。在推导方差之后，本说明回顾了两种检验之间的关系。F统计量具有充分充分性和易于表示幂函数的优点。当样本量超过20时，其偏倚可忽略不计。
For populations in which the genotypic frequencies are estimated, it is customary to test the deviation of the estimates from those predicted by the Hardy-Weinberg Law using the x2goodness-of-fit statistic. Maximum likelihood estimation ofWright'sF statisticand its variance furnishes a similar test. Following the derivation of the variance of, this note reviews the relation between the two tests. The F statistic possesses the advantages of full sufficiency and an easier formulation of the power function. Its bias is negligible when sample size exceeds 20.