Impact of abdominal compression on setup error and image matching during radical abdominal radiotherapy.
Impact of abdominal compression on setup error and image matching during radical abdominal radiotherapy.
复制标题
腹部压缩对腹部根治性放疗期间设置误差和图像匹配的影响。
DOI：
10.1016/j.tipsro.2019.11.003
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发表时间：
2019
影响因子：
--
通讯作者：
Chu KY
中科院分区：
文献类型：
--
作者：
Chu KY
目的探讨腹部压缩对图像匹配时间和设置误差的影响。材料与方法本研究纳入2016 - 2019年在单中心接受根治性治疗的72例肝、胰、腹结患者。患者接受SBRT或常规根治性分治（CRF）。受压患者仰卧，手臂向上，使用膝关节固定和AC设备。未压缩的患者仰卧，手臂向上，膝关节固定。所有患者在治疗前每天接受在线匹配的cbct。确定所有患者的初始设置误差。对10例肝脏和10例胰腺患者进行登记误差评估。利用光束照射时间确定图像匹配时间。进行的统计检验包括比较设置误差方差的f检验，设置误差和平均图像分析的学生t检验，以及成像匹配时间分析的Wilcoxon Mann Whitney检验。结果加压和未加压患者的初始复位位移相似。移位 > 1 cm在大多数患者中以纵向多见。SBRT患者在影像学检查后需要更多的手动定位。胰腺非压缩组和肝脏非压缩组SI方向的平均绝对配准误差分别为5.4 mm和3.3 mm，肝脏非压缩组和肝脏非压缩组分别为1.7 mm和0.8 mm。压缩患者所需的图像匹配时间更短，平均每个分数的图像更少。重复成像在SBRT和未压缩患者中更常见。结论腹部压迫术虽对术前设置误差无明显影响，但可减少影像学匹配次数，提高治疗精度。
PurposeTo determine the impact of abdominal compression (AC) on setup error and image matching time.Materials and methodsThis study included 72 liver, pancreas and abdominal node patients treated radically from 2016 to 2019 in a single centre. Patients received either SBRT or conventional radical fractionation (CRF). Compressed patients were supine, arms up with kneefix and AC equipment. Uncompressed patients were supine, arms up with kneefix. All patients received daily online-matched CBCTs before treatment. Initial setup error was determined for all patients. Registration error was assessed for 10 liver and 10 pancreas patients. Image matching times were determined using beam on times. Statistical tests conducted were an F-test to compare variances in setup error, Student’s t-tests for setup error and average image analysis, and a Wilcoxon Mann Whitney test for imaging matching time analysis.ResultsInitial setup displacement was similar between compressed and uncompressed patients. Displacements > 1 cm occurred more frequently in the longitudinal direction for most patients. SBRT patients required more additional manual positioning following imaging. Mean absolute registration error in the SI direction was 5.4 mm and 3.3 mm for uncompressed and compressed pancreas patients respectively and 1.7 mm and 0.8 mm for uncompressed and compressed liver patients respectively. Compressed patients required less time for image matching and fewer images per fraction on average. Repeat imaging occurred more frequently in SBRT and uncompressed patients.ConclusionsAlthough abdominal compression has no significant impact on setup error, it can reduce imaging matching times resulting in improved treatment accuracy.