Human psychopharmacology of hoasca, a plant hallucinogen used in ritual context in Brazil
Human psychopharmacology of hoasca, a plant hallucinogen used in ritual context in Brazil
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DOI：
10.1097/00005053-199602000-00004
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发表时间：
1996-02-01
影响因子：
1.9
通讯作者：
Boone, KB
中科院分区：
文献类型：
--
作者：
Grob, CS;McKenna, DJ;Boone, KB
1993 年夏天，针对死藤水（死藤水）（一种强效植物致幻剂混合物）的影响进行了一项多国合作的生物医学调查。这份报告描述了对一个融合教会的 15 名长期成员的心理评估，该教会利用死藤水作为合法的精神活性圣礼，以及 15 名之前没有摄入死藤水历史的对照对照。对两组进行的测量包括结构化的精神病诊断访谈、性格测试和神经心理学评估。对长期使用 hoasca 的组（而非未使用 hoasca 的对照组）进行了对改变的状态体验的现象学评估以及半结构化和开放式的生活故事访谈。显着的发现包括开始使用 hoasca 后精神病理学得到缓解，并且没有人格或认知恶化的证据。总体评估显示功能状态较高。讨论了这种不寻常现象的含义以及进一步调查的必要性。
A multinational, collaborative, biomedical investigation of the effects of hoasca (ayahuasca), a potent concoction of plant hallucinogens, was conducted in the Brazilian Amazon during the summer of 1993. This report describes the psychological assessment of 15 long-term members of a syncretic church that utilizes hoasca as a legal, psychoactive sacrament as well as 15 matched controls with no prior history of hoasca ingestion. Measures administered to both groups included structured psychiatric diagnostic interviews, personality testing, and neuropsychological evaluation. Phenomenological assessment of the altered state experience as well as semistructured and open-ended Life story interviews were conducted with the long-term use hoasca group, but not the hoasca-naive control group. Salient findings included the remission of psychopathology following the initiation of hoasca use along with no evidence of personality or cognitive deterioration. Overall assessment revealed high functional status. Implications of this unusual phenomenon and need for further investigation are discussed.