Measurement of Trabecular Bone Mineral by Dual Energy Computed Tomography
Measurement of Trabecular Bone Mineral by Dual Energy Computed Tomography
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双能计算机断层扫描测量骨小梁矿物质
DOI：
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发表时间：
1982
影响因子：
1.3
通讯作者：
Ian Isherwood
中科院分区：
文献类型：
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作者：
J. Adams;Chen Sz;P. Adams;Ian Isherwood
描述了脂肪对通过计算机断层扫描 (CT) 估计小梁骨矿物质浓度可能产生的影响的研究。使用同时双能技术在模拟骨小梁的模型和尸体股骨中测量计算机断层扫描衰减和有效原子序数。通过化学分析测量骨扫描区域的成分。在骨骼模型中。 CT衰减值和有效原子序数与钙浓度正相关：脂肪修正CT衰减值但与原子序数无关。小梁骨样品的钙浓度与有效原子序数呈正相关（r = 0.972；p < 0.001），并在较小程度上与 CT 衰减值呈正相关（r = 0.67；p < 0.01），但这两种关系均与脂肪无关。在这些实验条件下。通过双能 CT 确定有效原子序数比通过单能技术确定 Docs CT 衰减值可以更准确地测量小梁骨矿物质浓度。骨小梁间隙中骨组织数量存在相当大的空间变化，CT 衰减值随感兴趣区域的部位和大小而变化。准确配准对于通过 CT 精确测量小梁骨矿物质至关重要。
An investigation into the possible effect of fat on the estimation of trabecular bone mineral concentration by computed tomography (CT) is described. Computed tomographic attenuation and effective atomic number were measured in models simulating trabecular bone, and in cadaveric femora using a simultaneous dual energy technique. The composition of the area of bone scanned was measured by chemical analysis. In the bone models. CT attenuation value and effective atomic number were positively correlated to the calcium concentration: fat modified CT attenuation value but not atomic number. The calcium concentration of the trabecular bone samples was positively correlated with effective atomic number (r = 0.972; p < 0.001) and to a lesser extent with CT attenuation value (r = 0.67; p < 0.01), but both relations were independent of fat. Under the conditions of these experiments. the determination of effective atomic number by dual energy CT provides a more accurate measure of trabecular bone mineral concentration than docs CT attenuation value by a single energy technique. There was a considerable spatial variation in the amount of bone tissue in the trabecular bone space, and CT attenuation values varied with the site and size of the area of interest. Accurate registration is essential for the precise measurement of trabecular bone mineral by CT.