COMMON ANTIGENS BETWEEN ADULT SCHISTOSOMA MANSONI AND LABORATORY MOUSE
COMMON ANTIGENS BETWEEN ADULT SCHISTOSOMA MANSONI AND LABORATORY MOUSE
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DOI：
10.2307/3276622
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发表时间：
1967-01-01
影响因子：
1.3
通讯作者：
DAMIAN, RT
中科院分区：
文献类型：
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作者：
DAMIAN, RT
研究表明，成年曼氏血吸虫和宿主白化小鼠之间存在共同抗原。 Ouchterlony 技术使用抗血吸虫兔血清来比较血吸虫提取物和小鼠血清测试抗原，揭示了至少 4 种常见抗原。此外，针对全蠕虫匀浆制备的兔抗血清能够凝集小鼠红细胞。最后，发现抗血吸虫血清中羊溶血水平升高，表明蠕虫中存在福斯曼抗原。众所周知，福斯曼抗原也存在于小鼠体内，这使其成为另一种共享抗原。线虫中常见抗原的起源仍然未知。
Common antigens are shown to exist between adult Schistosoma mansoni and a host, the albino mouse. The Ouchterlony technique, in which anti-schistosome rabbit sera are used to compare schistosome extract and mouse serum test antigens, reveals at least 4 common antigens. Furthermore, rabbit antisera prepared against whole worm homogenates are able to agglutinate mouse erythrocytes. Finally, anti-schistosome sera are found to contain increased levels of sheep hemolysis, indicative of the Forssman antigen in the worm. The Forssman antigen is also known to be present in the mouse, making it another shared antigen. The origins of the common antigens in the worm are still unknown.