A novel approach to data collection in a case-control study of cancer and occupational exposures
A novel approach to data collection in a case-control study of cancer and occupational exposures
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DOI：
10.1093/ije/25.4.744
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发表时间：
1996-08-01
影响因子：
7.7
通讯作者：
Inskip, PD
中科院分区：
文献类型：
--
作者：
Stewart, PA;Stewart, WF;Inskip, PD
背景资料。在以社区和医院为基础的病例对照研究中，访谈中收集的职业数据通常仅限于对所有研究对象提出的一般问题的回答。描述了一种能够以高效、规范和系统的方式收集更详细信息的程序。最初使用计算机辅助面试从所有受试者收集一般工作历史。工作经历包括职称、业务类型、工作活动、材料和化学品以及使用的工具和设备。在面试官将回答输入计算机后，计算机搜索同义词文件以识别与所报告的工作相关的可能的工作特定模块。这些模块是详细的调查问卷，涉及在获得一般工作历史后管理的特定工作。这些单元用于询问以下问题：工作环境；接触来源；影响试剂从来源移动到受试者的因素，如局部排气通风；以及个人和工作特征。面谈完成后，工作历史和对模块的回复将以电子方式发送给工业卫生员，后者使用定制设计的软件包审查信息。在被调查者报告的信息中出现模棱两可或矛盾的情况下，或对于没有开发模块的工作，工业卫生员会为每个工作产生最多10个额外的问题。这些问题被送回面试官，以便进行简短的第二次面试。结论。这些程序正在一项正在进行的脑肿瘤病例对照研究中成功实施，与采用更传统的暴露评估方法得出的程序相比，这些程序应该会改善疾病风险估计。
Background. In community and hospital-based case-control studies, the occupational data collected in interviews are usually limited to responses to general questions asked of all study subjects. A procedure is described in which more detailed information can be collected in an efficient, standardized and systematic way.Methods. A generic work history is initially collected from all subjects using a computer-assisted interview. The work history includes job title, type of business, job activities, materials and chemicals, and tools and equipment used. After responses are entered into the computer by the interviewer, the computer searches a synonym file to identify possible job-specific modules relevant to the reported job. The modules are detailed questionnaires that address specific jobs administered after obtaining the generic work history. The modules are used to ask questions about the work environment; sources of exposure; factors affecting the movement of the agent from the source to the subject, such as local exhaust ventilation; and individual and job characteristics. After the interview is completed, the work history and responses to the modules are sent electronically to an industrial hygienist who reviews the information using a custom-designed software package. Where ambiguities or contradictions occur in information reported by the respondent, or for jobs for which no module had been developed, the industrial hygienist generates up to 10 additional questions per job. These questions are sent back to the interviewer for administration of a short, second interview.Conclusions. These procedures, which are being successfully implemented in an on-going case-control study of brain tumours, should improve disease risk estimates over those derived from more traditional approaches to exposure assessment.