Inhibitors for distinction of three types of human glutathione transferase

Inhibitors for distinction of three types of human glutathione transferase
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区分三种类型人谷胱甘肽转移酶的抑制剂

DOI:
10.1016/0014-5793(85)80269-6
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发表时间:
1985
期刊:
影响因子:
3.5
通讯作者:
B. Mannervik
B. Mannervik
中科院分区:
生物学3区
文献类型:
--
作者:
Mohammad Kalim Tahir;C. Guthenberg;B. Mannervik

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一组抑制剂,是用于区分三种类型的人胞浆谷胱甘肽转移酶。Cibacron蓝(itI50= 0.05 μM)对近中性转移酶的抑制作用最强,Cibacron蓝(itI50= 0.5 μM)对酸性转移酶的抑制作用最强,醋酸三丁基锡(itI50= 0.1 μM)对碱性转移酶的抑制作用最强。使用这两种化合物中的任何一种都可以区分所有三种类型的人转移酶。
A set of inhibitors that are useful for distinction of three types of human cytosolic glutathione transferase is presented. The near-neutral transferase is inhibited most effectively by Cibacron blue (itI50= 0.05 μM), the acidic transferase by Cibacron blue (itI50= 0.5 μM), and the basic transferase by tributyltin acetate (itI50= 0.1 μM). The use of any of these two compounds makes possible differentiation between all three types of human transferase.
人肝脏谷胱甘肽 S-转移酶阴离子和阳离子形式之间的相互关系。
DOI: 10.1042/bj1910001
发表时间: 1980
期刊: The Biochemical journal
影响因子: --
作者:
Awasthi,YC;Dao,DD;Saneto,RP
通讯作者: Saneto,RP