Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction - Prevalence and mortality in a population-based cohort

Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction - Prevalence and mortality in a population-based cohort
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DOI:
10.1016/s0735-1097(99)00118-7
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发表时间:
1999-06-01
影响因子:
24
通讯作者:
Levy, D
Levy, D
中科院分区:
医学1区
文献类型:
--
作者:
Vasan, RS;Larson, MG;Levy, D

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目的 本研究的目的是评估社区充血性心力衰竭 (CHF) 患者左心室 (LV) 收缩功能正常与受损的相对比例,并比较他们在随访期间的长期死亡率。 背景 几项基于医院的调查报告称,大部分 CHF 受试者的左心室收缩功能正常。社区中左心室收缩功能正常的 CHF 患病率和预后尚不清楚。 方法 我们评估了 73 名患有 CHF 的 Framingham 心脏研究受试者(33 名女性,40 名男性,平均年龄 73 岁)和 146 名年龄和性别匹配的对照受试者(巢式病例对照研究)的超声心动图。左心室收缩功能受损定义为左心室射血分数 (LVEF)
OBJECTIVES The purpose of this study was to assess the relative proportions of normal versus impaired left ventricular (LV) systolic function among persons with congestive heart failure (CHF) in the community and to compare their long-term mortality during follow-up.BACKGROUND Several hospital-based investigations have reported that a high proportion of subjects with CHF have normal LV systolic function. The prevalence and prognosis of CHF with normal LV systolic function in the community are not known.METHODS We evaluated the echocardiograms of 73 Framingham Heart Study subjects with CHF (33 women, 40 men, mean age 73 years) and 146 age- and gender-matched control subjects (nested case-control study). Impaired LV systolic function was defined as an LV ejection fraction (LVEF)