3D Printed Miniaturized Soft Microswimmer for Multimodal 3D Air-Liquid Navigation and Manipulation
3D Printed Miniaturized Soft Microswimmer for Multimodal 3D Air-Liquid Navigation and Manipulation
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DOI：
10.1109/mems49605.2023.10052220
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发表时间：
2023-01
期刊：
影响因子：
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通讯作者：
D. Decanini;A. Harouri;Ayako Mizushima;Beomjoon Kim;Y. Mita;G. Hwang
中科院分区：
文献类型：
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作者：
D. Decanini;A. Harouri;Ayako Mizushima;Beomjoon Kim;Y. Mita;G. Hwang
用于生物医学应用的微型游泳器的主要挑战可以列为气液导航的 3D 运动、多个游泳器的选择性运动控制、视觉伺服自动化控制和微操作功能。在这里，我们报告了一种微型软微型游泳器，可在气液环境中用作无线微型机器人操纵器。我们通过聚二甲基硅氧烷 (PDMS) 的双光子 3D 纳米打印和用于磁推进的铁磁镍层金属化来制造这些微米软游泳器。我们首次演示了利用磁力和浮力的多模态推进对多个软体游泳者进行 3D 气液导航和选择性运动控制。我们通过压电盘致动器施加高频振动，进一步减少了粘滑现象。这使得可以对软体微型游泳器进行实时视觉跟踪，并对微纤维进行显微操作。我们相信，这种 3D 打印和小型化移动代理应该将应用领域从体外微流体扩展到生物/化学测定。
Major challenges of microscale swimmers for biomedical applications could be listed as the 3D motion for air-liquid navigation, selective motion control of multiple swimmers, visual servo automation control and micromanipulation functionality. Here we report a miniaturized soft microswimmer for serving as a wireless microrobotic manipulator in air-liquid environments. We fabricated these micrometric soft swimmers by two-photon 3D nanoprinting of Polydimethylsiloxane (PDMS) and metallization of ferromagnetic nickel layer for magnetic propulsion. We demonstrated for the first time 3D air-liquid navigation and selective motion control of multiple soft swimmers thanks to the multimodal propulsion with magnetic and buoyancy force. We further reduced stick-slip phenomenon by applying high frequency vibration by piezo disc actuator. This allowed real-time visual tracking of the soft microswimmers and also the micromanipulation of microfibers. We believe that this 3D printed and miniaturized mobile agents should enlarge the application areas from in-vitro microfluidics to bio/chemical assay.