Ethanol-induced hypothermia and ethanol consumption in the rat are affected by low-level microwave irradiation.
Ethanol-induced hypothermia and ethanol consumption in the rat are affected by low-level microwave irradiation.
复制标题
乙醇引起的大鼠体温过低和乙醇消耗受到低强度微波照射的影响。
作者：
H. Lai;Akira Horita;Chung;Arthur W. Guy
用2450 MHz圆极化脉冲波(2微秒脉冲；500pps)在波导中对大鼠进行微波辐照，以确定对乙醇诱导的体温下降和乙醇消耗的影响。大鼠在微波辐射45min后立即腹腔注射乙醇(25%v/v水溶液中3g/kg)，可使乙醇引起的体温下降的初始速率减弱，但最大体温下降幅度与假照射组相比无显著差异。微波辐射不影响缺水大鼠对10%蔗糖(w/v)溶液的消耗。然而，它增加了缺水动物对10%蔗糖(w/v)+15%乙醇(v/v)溶液的消耗。这些结果是在比吸收率(SAR)为0.6W/kg时获得的，如果动物暴露在12厘米的平面波中，该能量剂量速率需要3-6 mW/cm2的功率密度。
Microwave irradiation of rats by circularly polarized, 2,450-MHz, pulsed waves (2-microseconds pulses; 500 pps) was performed in waveguides to determine effects on ethanol-induced hypothermia and on ethanol consumption. Rats injected intraperitoneally with ethanol (3 g/kg in a 25% v/v water solution) immediately after 45 min of microwave irradiation exhibited attenuation of the initial rate of fall in body temperature, which was elicited by the ethanol, but exhibited no significant difference in maximal hypothermia as compared with that of sham-irradiated rats. Microwave irradiation did not affect the consumption of a 10% sucrose (w/v) solution by water-deprived rats. However, it enhanced the consumption of a solution of 10% sucrose (w/v) + 15% ethanol (v/v) by water-deprived animals. These results were obtained at a specific absorption rate (SAR) of 0.6 W/kg, which rate of energy dosing would require a power density of 3-6 mW/cm2 if exposure of the animals had occurred to a 12-cm plane wave.