The peripheral immune response and lung cancer prognosis.
The peripheral immune response and lung cancer prognosis.
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DOI：
10.4161/onci.21096
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发表时间：
2012-11-01
期刊：
影响因子：
7.2
通讯作者：
Showe LC
中科院分区：
文献类型：
--
作者：
Showe MK;Kossenkov AV;Showe LC
最近已经报道了使用肿瘤基因表达来改进和改善结果预测的尝试。我们发现，外周血单核细胞（PBMC）相关的基因特征可以预测非小细胞肺癌患者的预后，而不依赖于人口统计学数据或TNM分期，并且这种信息可能在肿瘤切除后持续存在。
Attempts to refine and improve outcome predictions using tumor gene expression have been recently reported. We show that peripheral blood mononuclear cell (PBMC)-associated gene signatures can predict outcome in non-small cell lung carcinoma patients independent of demographic data or TNM staging, and that this information may persist after tumor resection.