Factors Inducing Retrograde Degeneration of the Cochlear Nerve
Factors Inducing Retrograde Degeneration of the Cochlear Nerve
复制标题
诱发耳蜗神经逆行性变性的因素
DOI：
10.1177/00034894840930s415
复制
发表时间：
1984
期刊：
影响因子：
--
通讯作者：
H. Spoendlin
中科院分区：
文献类型：
--
作者：
H. Spoendlin
描述了逆行性继发性变性的过程，并对其机制进行了讨论。在动物实验和人类颞骨中呈现了中央或外周轴突横断后以及Corti器官的各种类型损伤后的变性程度，包括变性的时间过程。最具实际意义的是由Corti器官的改变引起的继发性神经元变性。外毛细胞、内毛细胞、Corti中的支持结构以及神经末梢或外周树突的损伤的影响被分析并与不同类型的内耳疾病相关。
The process of retrograde secondary degeneration is described and its mechanism discussed. The extent of degeneration following transection of the central or peripheral axon and following various types of damage to the organ of Corti, including the time course of degeneration, is presented in animal experimentation and human temporal bones. Of greatest practical importance is secondary neuronal degeneration induced by alteration in the organ of Corti. The effect of damage to the outer hair cells, inner hair cells, supporting structures in the Corti, and nerve endings or peripheral dendrites is analyzed and related to different types of inner ear disease.