Evaluating Clinical Features in Intracavitary Uterine Pathologies among Vietnamese Women Presenting with Peri-and Postmenopausal Bleeding: A Bicentric Observational Descriptive Analysis.
Evaluating Clinical Features in Intracavitary Uterine Pathologies among Vietnamese Women Presenting with Peri-and Postmenopausal Bleeding: A Bicentric Observational Descriptive Analysis.
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DOI：
10.4103/jmh.jmh_81_22
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发表时间：
2022-07
影响因子：
1.1
通讯作者：
Nguyen VT
中科院分区：
文献类型：
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作者：
Nguyen PN;Nguyen VT
腔内子宫病变（IUP）可能导致围绝经期和绝经后妇女阴道出血。特别是，由于恶性疾病对越南等中低收入国家中年妇女的质量以及医疗保健费用负担的不利影响，需要对恶性疾病进行调查。因此，通过这项研究，我们的目的是评估妇女围绝经期和绝经后出血的妇女宫内节育器的主要临床特征。这是一项于2016年6月至2019年6月在顺化大学医院和顺化中央医院进行的横断面观察性研究。研究对象为150名40岁以上的子宫内出血妇女。研究人群的平均年龄为51.51 ± 7.65岁。围月经期妇女最常见的症状是月经过多，占62.2%。除宫内出血外，54.7%的病例至少有一种其他功能性症状，分别为皮肤苍白（35.9%）和下腹部疼痛（31.3%）。子宫内膜增生（EH）是两组围绝经期和绝经后出血（PMB）中最常见的病理，分别为66.7%和51.7%。在PMB组中，EH后子宫内膜癌（EC）约占38.3%。我们的研究揭示了年龄、月经特征和糖尿病与恶性疾病的关系。其他因素似乎与EC相关性较小。月经过多是围月经期妇女最常见的异常子宫出血类型。除了阴道出血，其他症状如皮肤苍白，盆腔疼痛和疲劳也很常见。围绝经期妇女住院日长和住院前出血量显著高于绝经后妇女。年龄、月经特征和糖尿病增加了PMB妇女的EC风险。
Intracavitary uterine pathologies (IUPs) may be resulting in vaginal bleeding in perimenopausal and postmenopausal women. Especially, malignant disease needed to be investigated due to its adverse impact on the quality of mid-life women as well as the burden of health-care costs in low- and middle-income countries such as Vietnam. Thereby, through this study, we aimed to assess the major clinical features of IUPs in women with perimenopausal and postmenopausal bleeding women. This was a cross-sectional observational study at Hue University Hospital and Hue Central Hospital from June 2016 to June 2019. The study enrolled 150 women above 40 years old involving with intrauterine bleeding. The mean age of the study population was 51.51 ± 7.65. The most common symptom in perimenopausal women was menorrhagia, up to 62.2% of cases. In addition to intrauterine bleeding, there were 54.7% of cases had at least one other functional symptom, they were pale skin (35.9%), and lower abdominal pain (31.3). Endometrial hyperplasia (EH) was the most common pathology in both groups with perimenopausal and postmenopausal bleeding (PMB), respectively, 66.7% and 51.7%. In PMB group, endometrial cancer (EC) occupied approximately 38.3% following EH. Our study revealed age, menstrual characteristics, and diabetes in relation to malignant disease. Other factors seemed to be less associated with EC. Menorrhagia was the most common type of abnormal uterine bleeding in perimenopausal women. Besides vaginal bleeding, others symptoms such as pale skin, pelvic pain, and fatigue were also common. Length day and blood loss before hospitalization in perimenopausal women were greater significantly than that in postmenopausal women. Age, menstrual characteristics, and diabetes increased the risk of EC in women with PMB.