Histologic changes in continuous, long-term electrical stimulation of a peripheral nerve.
Histologic changes in continuous, long-term electrical stimulation of a peripheral nerve.
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周围神经持续、长期电刺激的组织学变化。
DOI：
10.1109/tbme.1967.4502479
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发表时间：
1967
期刊：
影响因子：
--
通讯作者：
A. Kantrowitz
中科院分区：
文献类型：
--
作者：
P. Hershberg;D. Sohn;G. Agrawal;A. Kantrowitz
在过去，周围神经的慢性刺激通常是间歇性的或相对短期的。已发生的组织学变化可归因于机械因素和/或电荷作用引起的创伤。研究人员推测电刺激的影响，专门设计了电极，以尽量减少组织损伤。本研究的目的是确定哪些病理改变，如果有的话，是由电刺激引起的？不同于机械因素。狗被分成两组，只有那一组不同？控制?在膈神经周围植入电极，但从未使用过刺激。试验持续时间长达308天。结果表明，与机械损伤相比，电刺激对膈神经没有明显的组织学改变。
The chronic stimulation of peripheral nerves has, in the past, usually been of an intermittent or relatively short-term nature. Histologic changes which have taken place have been attributed to the trauma caused by mechanical factors and/or the effects of electrical charges. Investigators, speculating on the effects of electro-stimulation, have designed electrodes specifically to minimize tissue damage. The purpose of the present investigation is to determine which pathologic alterations, if any, are caused specifically by electrical?as distinct from mechanical?factors. Dogs were divided into two groups, differing only in that one group?the controls?had electrodes implanted around the phrenic nerve, but stimulation was never applied. Duration of the test was up to 308 days. The results indicated that no histologic alterations could be attributed specifically to electrical stimulation, as contrasted to mechanical trauma, to the phrenic nerve.