Quality matters: resource quality for hosts and the timing of epidemics
Quality matters: resource quality for hosts and the timing of epidemics
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DOI：
10.1111/j.1461-0248.2008.01264.x
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发表时间：
2009-02-01
期刊：
影响因子：
8.8
通讯作者：
Caceres, Carla E.
中科院分区：
文献类型：
--
作者：
Hall, Spencer R.;Knight, Christine J.;Caceres, Carla E.
流行病学家越来越认识到，物种间的相互作用（例如选择性捕食）可以决定流行病何时开始和结束。我们在这里假设，资源质量也可以强烈地影响疾病的动态：流行病可以被抑制时，主机的资源质量太差和太好。在三个湖泊，资源质量的浮游动物宿主（Daphnia dentifera）是穷人时，真菌流行病（Metschnikowia bicuspidata）开始和增加的流行减弱。利用藻类食物的变化进行的实验表明，资源质量对潜在的流行病学有相互矛盾的影响：高质量的食物会导致大量的感染性繁殖体（孢子）和高出生率，但也会减少传播。然后，一个模型说明了这些潜在的相关性如何抑制流行病的开始（当孢子产生/出生率过低时），但也催化了它们的结束（当传播变得过低时）。这种资源质量机制可能与其他控制疾病动态的机制相互作用，需要进行更密切的评价。
Epidemiologists increasingly realize that species interactions (e.g. selective predation) can determine when epidemics start and end. We hypothesize here that resource quality can also strongly influence disease dynamics: epidemics can be inhibited when resource quality for hosts is too poor and too good. In three lakes, resource quality for the zooplankton host (Daphnia dentifera) was poor when fungal epidemics (Metschnikowia bicuspidata) commenced and increased as epidemics waned. Experiments using variation in algal food showed that resource quality had conflicting effects on underlying epidemiology: high-quality food induced large production of infective propagules (spores) and high birth rate but also reduced transmission. A model then illustrated how these underlying correlations can inhibit the start of epidemics (when spore production/birth rate are too low) but also catalyse their end (when transmission becomes too low). This resource quality mechanism is likely to interface with other ones controlling disease dynamics and warrants closer evaluation.