The burden of late-life generalized anxiety disorder: effects on disability, health-related quality of life, and healthcare utilization.
The burden of late-life generalized anxiety disorder: effects on disability, health-related quality of life, and healthcare utilization.
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晚期普遍焦虑症的负担：对残疾，与健康相关的生活质量和医疗保健利用的影响。
DOI：
10.1097/jgp.0b013e31819b87b2
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发表时间：
2009-06
期刊：
影响因子：
--
通讯作者：
Lenze EJ
中科院分区：
文献类型：
--
作者：
Porensky EK;Dew MA;Karp JF;Skidmore E;Rollman BL;Shear MK;Lenze EJ
描述广泛性焦虑障碍（GAD）的负担，这是老年人常见的焦虑障碍。横截面。宾夕法尼亚州匹兹堡的老年抑郁和焦虑研究诊所。164名患有广泛性焦虑症的老年人和42名没有精神疾病史的健康对照者从初级保健和心理健康机构以及广告中招募。用晚年功能和残疾指数评估参与者的残疾，用MOS 36项简短问卷调查工具评估健康相关生活质量（HRQOL），用康奈尔服务指数评估医疗保健利用。即使在没有精神合并症的情况下，患有广泛性焦虑症的老年人比没有焦虑的参与者更残疾，HRQOL更差，医疗保健利用率更高。在控制医疗负担和抑郁症状后，焦虑症状的严重程度越高，在几个领域的残疾程度越高，HRQOL越差。在评估角色功能（包括社会功能）的测量中，观察到HRQOL和功能的最大下降。这项研究是迄今为止对老年人广泛性焦虑症进行的规模最大的研究，为这种疾病在晚年的重大负担提供了证据。鉴于广泛性焦虑症在老年人中的高患病率和慢性性，这些数据为寻找和实施有效的管理策略提供了公共卫生的必要性，这种疾病通常未被诊断和治疗。
To describe the burden of Generalized Anxiety Disorder (GAD), a common anxiety disorder in older adults. Cross-sectional. Late-life depression and anxiety research clinic in Pittsburgh, PA. One hundred sixty-four older adults with GAD and 42 healthy comparison participants with no lifetime history of psychiatric disorder were recruited from primary care and mental health settings as well as advertisements. Participants were evaluated with the Late Life Function and Disability Index to assess disability, the MOS 36-Item Short Form Survey Instrument to assess health-related quality of life (HRQOL), and the Cornell Service Index to assess healthcare utilization. Older adults with GAD were more disabled, had worse HRQOL, and had greater healthcare utilization, than nonanxious comparison participants, even in the absence of psychiatric comorbidity. After controlling for medical burden and depressive symptoms, higher severity of anxiety symptoms was associated with greater disability and poorer HRQOL in several domains. The greatest decrements in HRQOL and function were observed in measures assessing role functioning, including social function. This study, the largest ever of GAD in older adults, provides evidence of the significant burden of this disorder in late life. Given the high prevalence and chronicity of GAD in the elderly, these data provide a public health imperative for finding and implementing effective management strategies for this typically undiagnosed and untreated disorder.
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影响因子：
6.6
作者：
Dombrovski, Alexandre Y.;Mulsant, Benoit H.;Reynolds, Charles F., III
通讯作者：
Reynolds, Charles F., III
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
6.9
作者：
de Beurs, E;Beekman, ATF;van Tilburg, W
通讯作者：
van Tilburg, W
DOI：
10.1093/gerona/57.4.m209
发表时间：
2002-04-01
影响因子：
5.1
作者：
Jette, AM;Haley, SM;Ashba, J
通讯作者：
Ashba, J
影响因子：
7.2
作者：
Benitez, Carlos Israel Perez;Smith, Kevin;Keller, Martin B.
通讯作者：
Keller, Martin B.