Cross-Calibration of Prodigy and Horizon A Densitometers and Precision of the Horizon A Densitometer
Cross-Calibration of Prodigy and Horizon A Densitometers and Precision of the Horizon A Densitometer
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DOI：
10.1016/j.jocd.2021.02.003
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发表时间：
2021-08-03
影响因子：
2.5
通讯作者：
Dawson-Hughes, Bess
中科院分区：
文献类型：
--
作者：
Reitshamer, Elise;Barrett, Kelsey;Dawson-Hughes, Bess
我们进行这项研究是为了使临床研究参与者和患者能够可靠地从GE Lunar Prodigy过渡到Hologic Horizon a双能x射线吸收仪（DXA）扫描仪，并评估在新DXA扫描仪上进行测量的可重复性。45名老年人在Prodigy双能x线吸收仪（DXA）扫描仪上进行了一次脊柱、髋关节和全身扫描，在新的Hologic Horizon a DXA扫描仪上进行了两次脊柱、髋关节和全身扫描，并重新定位。采用线性回归模型推导出2台扫描仪上各测量值的交叉校准方程。使用国际临床密度测定学会（ISCD）高级精确计算工具评估全髋、股骨颈和腰椎（L1-L4）的骨密度（BMD）、体脂、骨、瘦质量、阑尾瘦质量和小梁骨评分（TBS）的精度（组均方根平均变异系数）。2台扫描仪测量的骨密度和身体成分的相关系数在0.94 ~ 0.99之间
We performed this study to enable a reliable transition for clinical study participants and patients from a GE Lunar Prodigy to a Hologic Horizon A dual-energy X-ray absorptiometry (DXA) scanner and to assess the reproducibility of measurements made on the new DXA scanner. Forty-five older adults had one spine, hip, and total body scan on a Prodigy dual-energy X-ray absorptiometry (DXA) scanner and 2 spine, hip, and total body scans, with repositioning, on a new Hologic Horizon A DXA scanner. Linear regression models were used to derive cross calibration equations for each measure on the 2 scanners. Precision (group root-mean-square average coefficient of variation) of bone mineral density (BMD) of the total hip, femoral neck, and lumbar spine (L1-L4), and total body fat, bone, and lean mass, appendicular lean mass, and trabecular bone score (TBS) was assessed using the International Society of Clinical Densitometry's (ISCD's) Advanced Precision Calculation Tool. Correlation coefficients for the BMD and body composition measures on the 2 scanners ranged from 0.94 to 0.99 (p