Synthesis of Allene-containing Apocarotenoids by Cross-coupling Strategy
Synthesis of Allene-containing Apocarotenoids by Cross-coupling Strategy
复制标题
交叉偶联策略合成含丙二烯的类胡萝卜素
DOI：
10.1055/s-0040-1707906
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
S. Katsumura
中科院分区：
文献类型：
--
作者：
K. Sakaguchi;Y. Nishioka;N. Kinashi;N. Yukihira;T. Shinada;T. Nishimura;H. Hashimoto;S. Katsumura
立体控制的全合成的丙二烯和羰基共轭阿朴胡萝卜素，paracentrone和19-hexanoyloxyparacentrone 3-乙酸酯，实现了通过顺序的交叉偶联反应，使用硼酸酯和碘或锡取代的C5二烯，这是建筑块的共轭多烯系统在两端的延长。
The stereocontrolled total synthesis of the allene and carbonyl conjugated apocarotenoids, paracentrone and 19-hexanoyloxyparacentrone 3-acetate, was achieved by sequential cross-coupling reactions using boronic acid ester and iodine- or tin-substituted C5 dienes, which were the building blocks for the elongation of the conjugated polyene systems at both terminals.