Habitual snoring with and without obstructive sleep apnoea: the importance of cephalometric variables.
Habitual snoring with and without obstructive sleep apnoea: the importance of cephalometric variables.
复制标题
伴有或不伴有阻塞性睡眠呼吸暂停的习惯性打鼾：头影测量变量的重要性。
作者：
Marco Zucconi;L. Ferini;Stefano Palazzi;Corrado Orena;Stefano Zonta;Salvatore Smime
背景技术背景：阻塞性睡眠呼吸暂停综合征的特征是睡眠期间呼吸暂停-低通气指数增加和最低动脉血氧饱和度（SaO 2）值降低。在何种程度上，这些变量可以预测头影测量和耳鼻咽喉变量进行了测试。方法：研究了100名连续的习惯性打鼾者（84%为男性），平均（SD）年龄为50.1（10.1）岁。将45名睡眠呼吸暂停不太严重的患者（呼吸暂停-低通气指数为10或更低）（A组）与55名指数大于10的患者（B组）进行比较。研究结果：A组和B组之间的体重指数、一些头影测量变量和一些耳鼻咽喉科变量存在显著差异，特别是软组织测量PNS-P（鼻后棘至腭）、MP-H（下颌平面至舌骨）、口咽狭窄程度和舌大小。在多元回归相关分析中，MP-H、SNB（从鞍点到鼻根点到棘下点的角度）、SNA（从鞍点到鼻根点到颏上点的角度）、PAS（后气道间隙）、舌头大小和体重指数对解释睡眠呼吸暂停严重程度的方程有显著贡献。然而，这些变量加在一起仅解释了总样本中呼吸暂停-呼吸不足指数方差的33%;它们对中度至重度疾病患者更为重要。结论：头影测量变量和轻度睡眠呼吸暂停之间缺乏相关性表明，这些变量（软组织测量）的差异可能是习惯性打鼾和阻塞性睡眠呼吸暂停综合征的结果，而不是原因。
BACKGROUND: The obstructive sleep apnoea syndrome is characterised by an increased apnoea-hypopnoea index and a reduction in the minimal arterial oxygen saturation (SaO2) values during sleep. The extent to which these variables can be predicted by cephalometric and otorhinolaryngological variables was tested. METHODS: One hundred consecutive habitual snorers (84% male), with a mean (SD) age of 50.1 (10.1) years, were studied. The 45 patients with less severe sleep apnoea, with an apnoea-hypopnoea index of 10 or less (group A), were compared with the 55 with an index above 10 (group B). RESULTS: Body mass index, some cephalometric variables, and some otorhinolaryngological variables differed significantly between group A and group B, in particular the soft tissue measures PNS-P (posterior nasal spine to palate), MP-H (mandibular plane to hyoid bone), degree of oropharynx stenosis, and tongue size. In a multiple regression correlation analysis MP-H, SNB (angle from sella to nasion to subspinale point), SNA (angle from sella to nasion to supramentale point), PAS (posterior airway space), tongue size, and body mass index contributed significantly to the equation explaining the severity of sleep apnoea. Nevertheless, these variables together explained only 33% of the variance of the apnoea-hypopnoea index in the total sample; they were more important for patients with moderate to severe stages of the disease. CONCLUSION: The lack of association between cephalometric variables and mild sleep apnoea suggests that the differences in these variables (soft tissue measures) may be the consequence rather than the cause of habitual snoring and the obstructive sleep apnoea syndrome.
影响因子：
9.6
作者：
PARTINEN, M;GUILLEMINAULT, C;JAMIESON, A
通讯作者：
JAMIESON, A
阻塞性睡眠呼吸暂停综合征呼吸障碍和氧饱和度下降指数的决定因素。
DOI：
--
发表时间：
1988
期刊：
The European respiratory journal
影响因子：
--
作者：
Quera-Salva,MA;Guilleminault,C;Partinen,M;Jamieson,A
通讯作者：
Jamieson,A