NUT midline carcinoma as a primary lung tumor: a case report
NUT midline carcinoma as a primary lung tumor: a case report
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DOI：
10.21037/jtd.2017.11.50
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发表时间：
2017-12-01
影响因子：
2.5
通讯作者：
Zhao, Chuanduo
中科院分区：
文献类型：
--
作者：
Cao, Jiashun;Chen, Donghong;Zhao, Chuanduo
摘要睾丸中线癌是一种罕见的发生于中线结构的恶性肿瘤，如头颈部及纵膈。在2015年WHO肺肿瘤分类中，它被归类为“上皮肿瘤”。但由于临床资料有限，其生物学特性尚未得到充分认识。我们报告一个NUT中线癌的情况下，提出了作为一个原发性肺肿瘤。在没有任何新辅助治疗的情况下进行了阑尾切除术，结果证明是一次大体全切除。即使如此，预后也很差，无病生存期为2个月，总生存期为6个月。
NUT (nuclear protein in testis) midline carcinoma is a rare malignant tumor arising in midline structures, such as head, neck and mediastinum. In the 2015 WHO classification of lung tumours, it was categorized in "Epithelial tumors". However, because of limited clinical data, its biological features have not been fully recognized. We report a case of NUT midline carcinoma presented as a primary lung tumor. Pneumonectomy was performed without any neoadjuvant therapy and it turned out to be a gross total resection. Even so, the prognosis is poor with a disease-free survival of 2 months and an overall survival of 6 months.