Molecularly Responsive Binding through Co-occupation of Binding Space: A Lock-Key Story.

Molecularly Responsive Binding through Co-occupation of Binding Space: A Lock-Key Story.
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DOI:
10.1021/acs.orglett.6b00527
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发表时间:
2016-04-01
期刊:
影响因子:
5.2
通讯作者:
Zhao Y
Zhao Y
中科院分区:
化学1区
文献类型:
--
作者:
Awino JK;Hu L;Zhao Y

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当两个客体分子共同占据水溶性主体的结合袋时,第一个客体分子可以用作信号分子来开启第二个客体分子的结合。这种类型的分子响应结合很大程度上取决于两个客体的大小和信号分子的位置。
When two guest molecules co-occupy a binding pocket of a water-soluble host, the first guest could be used as a signal molecule to turn on the binding of the second. This type of molecularly responsive binding strongly depends on the size of the two guests and the location of the signal molecule.