National-scale simulation of human movement in a spatially coupled individual-based model of malaria in Burkina Faso.
National-scale simulation of human movement in a spatially coupled individual-based model of malaria in Burkina Faso.
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DOI：
10.1038/s41598-022-26878-5
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发表时间：
2023-01-06
影响因子：
4.6
通讯作者：
中科院分区：
文献类型：
--
作者：
尽管做出了根除努力并开发了青蒿素联合疗法等抗疟疾治疗方法，但由恶性疟原虫引起的疟疾仍然对人类健康构成威胁。人类移动和移民与全国范围内疟疾的传播有关，这凸显了将人类移动纳入建模工作的必要性。基于个体的空间耦合模型已被用来研究抗疟疾耐药性如何随着药物政策的变化而演变和传播；然而，随着模型空间规模的增加，与运动建模相关的挑战也随之增加。在本文中，我们讨论了在用于研究疟原虫耐药性进化的国家规模、空间、基于个体的模型背景下运动模型的开发、校准和验证。
Malaria due to the Plasmodium falciparum parasite remains a threat to human health despite eradication efforts and the development of anti-malarial treatments, such as artemisinin combination therapies. Human movement and migration have been linked to the propagation of malaria on national scales, highlighting the need for the incorporation of human movement in modeling efforts. Spatially couped individual-based models have been used to study how anti-malarial resistance evolves and spreads in response to drug policy changes; however, as the spatial scale of the model increases, the challenges associated with modeling of movement also increase. In this paper we discuss the development, calibration, and validation of a movement model in the context of a national-scale, spatial, individual-based model used to study the evolution of drug resistance in the malaria parasite.
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DOI：
10.1371/journal.pgph.0000111
发表时间：
2022
期刊：
PLOS global public health
影响因子：
--
作者：
通讯作者：
--
DOI：
10.4269/ajtmh.2004.71.94
发表时间：
2004-08-01
影响因子：
3.3
作者：
McKenzie, FE;Samba, EM
通讯作者：
Samba, EM
影响因子：
3
作者：
Marshall JM;Touré M;Ouédraogo AL;Ndhlovu M;Kiware SS;Rezai A;Nkhama E;Griffin JT;Hollingsworth TD;Doumbia S;Govella NJ;Ferguson NM;Ghani AC
通讯作者：
Ghani AC
DOI：
10.1098/rspb.2002.2241
发表时间：
2003-03-07
影响因子：
4.7
作者：
White, NJ;Pongtavornpinyo, W
通讯作者：
Pongtavornpinyo, W
影响因子：
4.9
作者：
Henry, S;Boyle, P;Lambin, EF
通讯作者：
Lambin, EF