Neurotransmitter Release from the Medial Hyperstriatum Ventrale of the Chick Forebrain Accompanying Filial Imprinting Behavior, Measured by In Vivo Microdialysis
Neurotransmitter Release from the Medial Hyperstriatum Ventrale of the Chick Forebrain Accompanying Filial Imprinting Behavior, Measured by In Vivo Microdialysis
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通过体内微透析测量伴随子女印记行为的鸡前脑内侧上纹状体腹侧的神经递质释放
DOI：
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发表时间：
1999
影响因子：
4.4
通讯作者：
Hiromi Takahara
中科院分区：
文献类型：
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作者：
Y. Tsukada;T. Kanamatsu;Hiromi Takahara
鸡的印记行为被量化为在转轮装置中获得的偏好分数(正确响应率)。共有249只雏鸡被暴露在印记刺激下，并测试其接近刺激的行为。然后将这些雏鸡分为学习良好(印记)、学习差(非印记)和灰色地带组，分别占总雏鸡的46%、31%和23%。用在体微透析法测定鸡前脑内侧纹状体腹侧区(MHV)的乙酰胆碱(ACh)和谷氨酸(Glu)的释放。以非印迹雏鸡为对照。印迹雏鸡在印迹刺激过程中ACh和谷氨酸的释放增加，而非印迹雏鸡在印迹刺激过程中这些神经递质的释放没有变化。这些结果可能表明，胆碱能和谷氨酸能突触是在MHV内形成的具有印记刺激的功能性突触，它们参与了印记行为的执行。
The imprinting behavior of chicks was quantified as a preference score (correct response ratio) achieved in a running wheel apparatus. A total of 249 chicks were exposed to an imprinting stimulus and tested for stimulus-approaching behavior. The chicks were then classified as good learners (imprinted), poor learners (non-imprinted) and a gray-zone group, those were 46%, 31% and 23% of the total chicks respectively. Using the classified chicks, the acetylcholine (ACh) and glutamate releases from the medial hyperstriatum ventrale (MHV) of the chick forebrains were determined by in vivo microdialysis. The non-imprinted chicks were used as yoked controls. Increases of ACh and glutamate released were observed in the imprinted chicks during exposure to the imprinting stimulus, whereas there were no changes in the release of these neurotransmitters in the non-imprinted chicks during the imprinting exposure. These results might be indicated that cholinergic and glutamatergic synapses which are newly formed as functioning synapses with imprinting stimulus in the MHV are involved in the performance of imprinting behavior.