Differential effect of reward and punishment on procedural learning.
Differential effect of reward and punishment on procedural learning.
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DOI：
10.1523/jneurosci.4132-08.2009
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发表时间：
2009-01-14
期刊：
影响因子：
--
通讯作者：
Ashe J
中科院分区：
文献类型：
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作者：
Wächter T;Lungu OV;Liu T;Willingham DT;Ashe J
奖惩是工具性和经典性条件性联想学习的有力调节器。然而，奖惩对程序性学习的影响尚不清楚。众所周知，纹状体是奖赏相关神经信号的重要场所，也是程序性学习的神经底物的一部分。在这里，使用内隐的运动学习任务，我们表明奖励导致人类受试者学习的增强，而惩罚只与运动表现的改善有关。此外，这些行为效应有不同的神经基础，奖赏的学习效应通过背侧纹状体传递，惩罚的执行效应通过脑岛传递。我们的结果表明，奖励和惩罚涉及不同的动机系统，具有不同的行为影响和神经基础。
Reward and punishment are potent modulators of associative learning in instrumental and classical conditioning. However, the effect of reward and punishment on procedural learning is not known. The striatum is known to be an important locus of reward-related neural signals and part of the neural substrate of procedural learning. Here, using an implicit motor learning task, we show that reward leads to enhancement of learning in human subjects, whereas punishment is associated only with improvement in motor performance. Furthermore, these behavioral effects have distinct neural substrates with the learning effect of reward being mediated through the dorsal striatum and the performance effect of punishment through the insula. Our results suggest that reward and punishment engage separate motivational systems with distinctive behavioral effects and neural substrates.