Enhancement of diagnostic efficiency by a gamma interferon release assay for pulmonary tuberculosis
Enhancement of diagnostic efficiency by a gamma interferon release assay for pulmonary tuberculosis
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DOI：
10.1128/cvi.00026-08
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发表时间：
2008-06-01
影响因子：
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通讯作者：
Ferreira, Antonio Walter
中科院分区：
文献类型：
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作者：
Kanunfre, Kelly Aparecida;Munhoz Leite, Olavo Henrique;Ferreira, Antonio Walter
本研究旨在检查使用QuantiFERON-TB Gold检测试剂盒辅助诊断巴西患者的活动性肺结核（TB）。使用受试者工作特征曲线，将截止值调整为>= 0.20 IU/ml。敏感性提高到86%，特异性为100%。所有痰涂片镜检阴性和培养结果阴性的结核病患者均为阳性。
This study was designed to examine the use of the QuantiFERON-TB Gold assay as an aid in the diagnosis of active pulmonary tuberculosis (TB) in Brazilian patients. Using the receiver operating characteristic curve, the cutoff was adjusted to >= 0.20 IU/ml. The sensitivity increased to 86%, with 100% specificity. All TB patients with negative sputum smear microscopy and negative culture results were positive using this test.