Use of pulsed Doppler tissue imaging to assess regional left ventricular diastolic dysfunction in hypertrophic cardiomyopathy
Use of pulsed Doppler tissue imaging to assess regional left ventricular diastolic dysfunction in hypertrophic cardiomyopathy
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DOI：
10.1016/s0002-9149(98)00648-1
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发表时间：
1998-12-01
影响因子：
2.8
通讯作者：
Mininni, N
中科院分区：
文献类型：
--
作者：
Severino, S;Caso, P;Mininni, N
本研究应用脉冲组织成像技术(DTI)研究肥厚型心肌病(HC)患者的局部舒张期血流频谱及其与二尖瓣血流频谱的关系。对20例HC患者(男15例，女5例)和10例健康体检者(男7例，女3例)进行了超声心动图和心尖四腔切面的室间隔及侧壁DTI检查。排除标准为糖尿病、高血压、冠状动脉和瓣膜疾病、二尖瓣返流、纽约心脏协会功能分级III至IV级、窦性心动过速、房颤和超声心动图检查不充分。应用标准多普勒和DTI技术测定室间隔和侧壁的峰值速度、时间-速度积分及其比值、减速时间和等容松弛时间。两组在年龄、罕见心脏、血压和射血分数方面具有可比性。二尖瓣峰值速度和时间-速度积分E/A比值降低(P均<0.05)。
In this study, regional diastolic patterns and their relations with transmitral Doppler inflow were investigated in hypertrophic cardiomyopathy (HC) by pulsed Doppler tissue imaging (DTI). Doppler echocardiography and DTI of basal septum and lateral wall (apical 4-chamber view) were performed in 20 patients (15 men and 5 women) with HC and in 10 healthy subiects (7 men and 3 women). Diabetes, hypertension, coronary artery and valvular disease, mitral regurgitation, New York Heart Association functional classes III to IV, sinus tachycardia, atrial fibrillation, and inadequate echocardiograms were exclusion criteria. Peak velocity and time-velocity integral of early and late waves and their ratios, and deceleration and isovolumic relaxation times were determined by standard Doppler and by DTI at the septal and lateral wall levels. The 2 groups were comparable for age, heart rare, blood pressure, and ejection fraction. Transmitral peak velocity and time-velocity integral E/A ratios were reduced (both p