DETERMINATION OF THE STRUCTURE OF THE ESCHERICHIA-COLI K100 CAPSULAR POLYSACCHARIDE, CROSS-REACTIVE WITH THE CAPSULE FROM TYPE-B HEMOPHILUS-INFLUENZAE

DETERMINATION OF THE STRUCTURE OF THE ESCHERICHIA-COLI K100 CAPSULAR POLYSACCHARIDE, CROSS-REACTIVE WITH THE CAPSULE FROM TYPE-B HEMOPHILUS-INFLUENZAE
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DOI:
10.1016/s0008-6215(00)90803-6
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发表时间:
1988-02-15
影响因子:
3.1
通讯作者:
ROBBINS, JB
ROBBINS, JB
中科院分区:
化学3区
文献类型:
--
作者:
TSUI, FP;EGAN, W;ROBBINS, JB

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The structure of the Escherichia coli K100 capsular polysaccharide, cross-reactive with that from type b Haemophilus influenzae, was determined by using a combination of chemical and spectroscopic technique. The structure of the K100 repeating unit was found to be .fwdarw.3)-.beta.-D-Ribf-(1.fwdarw.2)-D-ribitol-5-(PO4.fwdarw.. The K100 polysaccharide is thus identical in composition to, but different in linkage from, the H. influenzae type b capsular polysaccharide, which has .beta.-D-Ribf-(1.fwdarw.1)-D-ribitol linkages.