Pancreatic cancer associated with autoimmune pancreatitis in remission

Pancreatic cancer associated with autoimmune pancreatitis in remission
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DOI:
10.2169/internalmedicine.47.0334
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发表时间:
2008-01-01
期刊:
影响因子:
1.2
通讯作者:
Okazaki, Kazuichi
Okazaki, Kazuichi
中科院分区:
医学4区
文献类型:
--
作者:
Fukui, Toshiro;Mitsuyama, Toshiyuki;Okazaki, Kazuichi

文献摘要

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2007年1月,一位80岁的老人因胰脏肿瘤入院治疗。2003年12月,他被诊断为自身免疫性胰腺炎(AIP),类固醇治疗后病情缓解。2006年11月,肿瘤标志物水平迅速升高,根据影像学检查,患者怀疑患有胰腺癌。诊断后经内镜超声引导下细针穿刺活检证实。鉴别AIP与胰腺癌至关重要;然而,以前很少有报道描述任何与AIP相关的胰腺癌病例。虽然一些报道推测了AIP的预后,但该疾病的自然病程仍不确定。本报告强调AIP可以与癌症共存。
In January 2007, an 80-year-old man was admitted to our hospital for treatment of a pancreatic tumor. He had been diagnosed with autoimmune pancreatitis (AIP) in December 2003 for which steroid therapy had induced remission. In November 2006, tumor marker levels rapidly increased, and the patient was suspected of having pancreatic cancer based on imaging studies. The diagnosis was later confirmed by endoscopic ultrasound-guided fine-needle aspiration biopsy. Distinguishing AIP from pancreatic cancer is crucial; however, few previous reports have described any cases of pancreatic cancer associated with AIP. While several reports have speculated on the prognosis of AIP, natural courses of the disease remain uncertain. This report emphasizes that AIP can coexist with cancer.