Catalyst-Controlled Regiodivergent Dehydrogenative Heck Reaction of 4-Arylthiophene/Furan-3-Carboxylates
Catalyst-Controlled Regiodivergent Dehydrogenative Heck Reaction of 4-Arylthiophene/Furan-3-Carboxylates
复制标题
催化剂控制的 4-芳基噻吩/3-呋喃-3-羧酸酯区域发散脱氢 Heck 反应
DOI：
10.1002/adsc.201600696
复制
发表时间：
2016-12-01
影响因子：
5.4
通讯作者：
Yao, Hequan
中科院分区：
文献类型：
--
作者：
Gao, Shang;Wu, Zijun;Yao, Hequan
实现了4-芳基噻吩/呋喃-3-羧酸酯的催化剂控制的区域发散Heck反应。钯催化剂的使用导致通过电子钯化的C-5烯基化，而钌催化剂有利于C-2烯基化与导向基团的帮助。该反应表现出良好至优异的区域选择性。
A catalyst-controlled regiodivergent dehydrogenative Heck reaction of 4-arylthiophene/furan-3-carboxylates has been realized. Use of a palladium catalyst led to the C-5 alkenylation through electronic palladation, while a ruthenium catalyst favored the C-2 alkenylation with the assistance of a directing group. This reaction exhibited good to excellent regioselectivities.