Synthesis of (±)-Merrilactone A by a Desymmetrization Strategy
Synthesis of (±)-Merrilactone A by a Desymmetrization Strategy
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通过去对称化策略合成(±)-Merrilactone-A
DOI：
10.1002/chem.201804195
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Bo Wang
中科院分区：
文献类型：
--
作者：
Wentan Liu;Bo Wang
已经完成了（±）-merrilactone A的简洁合成，其特征在于aCs-对称双内酯的去对称化，RhI催化的4-炔醛的分子内加氢酰化，以及Ti III介导的环氧丙二烯的还原性自由基环化。
A concise synthesis of (±)‐merrilactone A has been accomplished featuring desymmetrization of aCs‐symmetric dilactone, RhI‐catalyzed intramolecular hydroacylation of a 4‐alkynal, and TiIII‐mediated reductive radical cyclization of epoxy‐allene.