Influential factors for pressure pulse waveform in healthy young adults.
Influential factors for pressure pulse waveform in healthy young adults.
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DOI：
10.3233/bme-151339
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发表时间：
2015
影响因子：
1
通讯作者：
Yi Du;Ling Wang;Shuyu Li;G. Zhi;Deyu Li;Chi Zhang
中科院分区：
文献类型：
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作者：
Yi Du;Ling Wang;Shuyu Li;G. Zhi;Deyu Li;Chi Zhang
性别和其他因素对脉搏波形的影响仍存在争议。鉴于对脉搏波可能的影响因素考虑较少以及性别对脉搏波特征的普遍认同而导致的结果不同，本研究旨在解决干扰性别与脉搏波特征关联的混杂因素。提出了一种无损检测压力脉搏波并评价脉搏波形态的新方法。本研究纳入40名健康青年受试者。手动测量身高、体重、收缩压(SBP)、舒张压(DBP)，自动计算体重指数(BMI)、脉压(PP)、心率(HR)。采用t检验分析性别差异，用方差分析检验内在因素的影响。对影响波形特征的主要因素进行单因素回归分析。波形特征在不同性别之间有显著差异。然而，本研究表明，时间相关参数和幅度相关参数的主要影响因素分别是心率和SBP。综上所述，HR和SBP对脉搏波特征的影响不可低估，尤其是在分析性别差异时。
The effects of gender and other contributory factors on pulse waveform are still under arguments. In view of different results caused by few considerations of possible influential factors and general agreement of gender relating to pulse waveform, this study aims to address the confounding factors interfering with the association between gender and pulse waveform characteristics. A novel method was proposed to noninvasively detect pressure pulse wave and assess the morphology of pulse wave. Forty healthy young subjects were included in the present research. Height, weight, systolic blood pressure (SBP), and diastolic blood pressure (DBP) were measured manually and body mass index (BMI), pulse blood pressure (PP) and heart rate (HR) were calculated automatically. Student's t test was used to analyze the gender difference and analysis of variance (ANOVA) to examine the effects of intrinsic factors. Univariate regression analysis was performed to assess the main factors on the waveform characteristics. Waveform features were found significantly different between genders. However this study indicates that the main factors for time-related and amplitude-related parameters are HR and SBP respectively. In conclusion, the impact of HR and SBP on pulse waveform features should not be underestimated, especially when analyzing the gender difference.