The first draft genomes of the ant Formica exsecta , and its Wolbachia endosymbiont reveal extensive gene transfer from endosymbiont to host
The first draft genomes of the ant Formica exsecta , and its Wolbachia endosymbiont reveal extensive gene transfer from endosymbiont to host
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蚂蚁Formica exsecta及其沃尔巴克氏体内共生体的基因组初稿揭示了从内共生体到宿主的广泛基因转移。
DOI：
10.1101/436691
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Dhaygude K
中科院分区：
文献类型：
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作者：
Dhaygude K
研究背景适应环境变化是物种生存的基础，通常认为是一个渐进的过程。然而，转座因子（TE）、表观遗传修饰和/或通过水平基因转移（HGT）从其他生物获得的遗传物质也可以导致新的适应性性状。群居昆虫形成密集的群落，吸引并维持细胞外和细胞内的附属居民，这可能有助于物种之间的基因转移。木蚁（Formica exsecta，蚁科，Hyuttera）是古北界常见的一种蚂蚁。该物种是一个完善的模式，生态特征和进化confliction.ResultsIn这项研究中，我们测序和组装草案基因组forF。外切带及其内共生菌Wolbachia. F。exsectadraft基因组是277.7 Mb长;我们确定了13，767个蛋白质编码基因，我们提供了基因本体和蛋白质结构域注释。这也是第一个从蚂蚁的Wolbachiagenome的报告，并提供了深入了解这种内共生体的系统发育位置。我们还确定了多个水平基因转移事件（HGT）从沃尔巴克氏体F。不全裂这些HGT中的一些也发生在多个其他昆虫基因组平行，突出HGT在真核生物的程度。exsecta，和它的内共生Wolbachia（wFex），并显示相当大的基因转移率从共生体到主机。我们希望，特别是F。外切基因组将是进一步探索社会组织进化的分子基础的宝贵资源。
BackgroundAdapting to changes in the environment is the foundation of species survival, and is usually thought to be a gradual process. However, transposable elements (TEs), epigenetic modifications, and/or genetic material acquired from other organisms by means of horizontal gene transfer (HGTs), can also lead to novel adaptive traits. Social insects form dense societies, which attract and maintain extra- and intracellular accessory inhabitants, which may facilitate gene transfer between species. The wood antFormica exsecta(Formicidae; Hymenoptera), is a common ant species throughout the Palearctic region. The species is a well-established model for studies of ecological characteristics and evolutionary conflict.ResultsIn this study, we sequenced and assembled draft genomes forF. exsectaand its endosymbiontWolbachia. TheF. exsectadraft genome is 277.7 Mb long; we identify 13,767 protein coding genes, for which we provide gene ontology and protein domain annotations. This is also the first report of aWolbachiagenome from ants, and provides insights into the phylogenetic position of this endosymbiont. We also identified multiple horizontal gene transfer events (HGTs) fromWolbachiatoF. exsecta. Some of these HGTs have also occurred in parallel in multiple other insect genomes, highlighting the extent of HGTs in eukaryotes.ConclusionWe present the first draft genome of antF. exsecta, and its endosymbiontWolbachia(wFex), and show considerable rates of gene transfer from the symbiont to the host. We expect that especially theF. exsectagenome will be valuable resource in further exploration of the molecular basis of the evolution of social organization.