Improvement of cardiac function and neurological remodeling in a patient with tachycardia-induced cardiomyopathy after catheter ablation
Improvement of cardiac function and neurological remodeling in a patient with tachycardia-induced cardiomyopathy after catheter ablation
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DOI：
10.1016/j.jjcc.2008.10.002
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发表时间：
2009-08-01
影响因子：
2.5
通讯作者：
Endo, Masahiro
中科院分区：
文献类型：
--
作者：
Omichi, Chikaya;Tanaka, Takeshi;Endo, Masahiro
持续的室性心动过速和长期的异位搏动导致心动过速引起的心肌病。导管消融可消除室性心动过速并逆转左心室功能障碍。201-铊（(201)Tl）显像显示缺血性心肌病的灌注缺陷。即使在非缺血性心肌病中也观察到可逆性灌注缺陷，这与局部血流或代谢紊乱有关。（123）I-metaiodobezykguanidine （(123)I-MIBG）显像描绘了区域心脏交感神经去支配和异质性。我们使用（201）Tl和（123）I-MIBG扫描结果证明了特发性W流出道心动过速患者的心动过速性心肌病的进展。在（2011）Tl和（123）I-MIBG扫描结果中，基底室间隔瓦的区域缺损主要逆转。本报告提示持续的室性心动过速或长期室性异位搏可能导致不良的心肌重构和交感神经重构。导管消融治疗心动过速性心肌病可以逆转交感神经重构和心肌结构重构。(C) 2008日本心脏病学会。爱思唯尔爱尔兰有限公司出版。版权所有。
Incessant ventricular tachycardia and long-standing ectopic beats lead to tachycardia-induced cardiomyopathy. Catheter ablation eliminates ventricular tachycardia and reverses left ventricular (W) dysfunction. 201-Thallium ((201)Tl) scintigraphy demonstrates perfusion defects with ischemic cardiomyopathy. Reversible perfusion defects are observed even in non-ischemic cardiomyopathy, related to regional flow or metabolism derangements. (123)I-metaiodobezykguanidine ((123)I-MIBG) scintigraphy delineates regional cardiac sympathetic denervation and heterogeneity. We demonstrated the progression of tachycardia-induced cardiomyopathy in a patient with idiopathic W outflow tract tachycardia using (201)Tl and (123)I-MIBG scintigraphic findings. Regional defects were reversed predominantly in the basal interventricular septal watt in (201)Tl scintigraphy and (123)I-MIBG scintigraphic findings. This report suggests that incessant ventricular tachycardia or tong-standing ventricular ectopic beats may develop adverse myocardial remodeling and sympathetic neurological remodeling. Treatment with catheter ablation for tachycardia-induced cardiomyopathy can reverse sympathetic neurological remodeling as well as myocardial structural remodeling. (C) 2008 Japanese College of Cardiology. Published by Elsevier Ireland Ltd. All rights reserved.