Suicidal ideation in pregnancy: assessment and clinical implications

Suicidal ideation in pregnancy: assessment and clinical implications
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DOI:
10.1007/s00737-007-0192-x
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发表时间:
2007-10-01
影响因子:
4.5
通讯作者:
Stowe, Z. N.
Stowe, Z. N.
中科院分区:
医学2区
文献类型:
--
作者:
Newport, D. J.;Levey, L. C.;Stowe, Z. N.

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本研究的目的是:1)确定有神经精神疾病史的孕妇自杀意念(SI)的患病率,2)评估常用抑郁量表检测SI的相对敏感性,3)检查孕妇SI的社会人口统计学和临床预测因素。人口统计学资料,贝克抑郁量表[BDI]和汉密尔顿抑郁量表[HRSD]问卷调查,和SCID访谈,从383名孕妇提出的埃默里妇女的心理健康计划或埃默里妇女的癫痫计划。在完成这两个量表的人中,29.2%的人赞同BDI的SI,16.9%的人赞同HRSD,33.0%的人赞同至少一个评级量表的SI,13.1%的人赞同两个评级量表。SI对BDI的支持率比HRSD高73.3%。多因素Logistic回归分析显示,妊娠期SI与计划外妊娠(OR = 2.97)、抑郁症(OR = 4.12)和焦虑障碍(OR = 4.17)有关。进一步的研究是必要的,以确定额外的围产期自杀倾向的预测因素,并澄清这些因素之间的关联的性质和存在SI孕妇。
The objectives of this study were 1) to determine the prevalence of suicidal ideation (SI) in pregnant women with a history of neuropsychiatric illness, 2) to assess the relative sensitivity of commonly used depression rating scales for detecting SI, and 3) to examine the sociodemographic and clinical predictors of SI in pregnant women. Demographic data, Beck Depression Inventory [BDI] and Hamilton Rating Scale for Depression [HRSD] questionnaires, and SCID interviews were obtained from 383 pregnant women presenting to the Emory Women's Mental Health Program or the Emory Women's Epilepsy Program. Among those who completed both scales, 29.2% endorsed SI on the BDI and 16.9% on the HRSD, with 33.0% endorsing SI on at least one of the rating scales and 13.1% on both rating scales. The rate of SI endorsement on the BDI was 73.3% higher than the HRSD. Multivariate logistic regression demonstrated that SI in pregnant women was associated with unplanned pregnancy (OR = 2.97), current major depression (OR = 4.12), and comorbid anxiety disorder (OR = 4.17). Further studies are warranted to identify additional predictors of perinatal suicidality and to clarify the nature of the association between such factors and the presence of SI in pregnant women.