Biogenic Synthesis and Spatial Distribution of Endogenous Phytohormones and Ginsenosides Provide Insights on Their Intrinsic Relevance in Panax ginseng
Biogenic Synthesis and Spatial Distribution of Endogenous Phytohormones and Ginsenosides Provide Insights on Their Intrinsic Relevance in Panax ginseng
复制标题
内源植物激素和人参皂苷的生物合成和空间分布提供了关于它们在人参中的内在相关性的见解
DOI：
10.3389/fpls.2018.01951
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发表时间：
2019-01-09
影响因子：
5.6
通讯作者：
Huang, Luqi
中科院分区：
文献类型：
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作者：
Chen, Kang;Liu, Juan;Huang, Luqi
人参，为Panax ginseng C. A. Mey.的根及根茎，是著名的名贵中药材。人参的药理活性主要归因于人参皂苷的存在，人参皂苷被认为是评价人参质量的关键生物标志物。在植物中发挥防御功能的三萜的生物合成受到内源植物激素的调节，内源植物激素在植物种群的生长和防御中发挥着关键作用。然而，人们对人参次生代谢途径密切相关的主要激素的作用知之甚少。为了深入了解它们之间的潜在相关性，我们进行了空间综合分析，并研究了内源植物激素和人参皂苷在整个人参植物不同组织区域中的分布。赤霉素是积累在纤维根中的生长激素。相比之下，脱落酸（ABA）、水杨酸（SA）和茉莉酸（JA）被认为是应激激素，主要存在于叶子和叶梗中。我们观察到植物激素的组织特异性分布与影响人参皂苷合成和分布的激素生物合成相关基因的表达一致。本研究的目的是探讨不同内源植物激素对人参天然免疫中三萜代谢物的作用。
Ginseng, the root and rhizome of Panax ginseng C. A. Mey., is a well-known and valuable traditional Chinese medicine. The pharmacological activities of ginseng are mainly attributed to the presence of ginsenosides, which are considered to be critical biomarkers for evaluating ginseng quality. The biosynthesis of triterpenes, which serve defensive functions in plants, is regulated by endogenous phytohormones that play key roles in growth and defense of plant populations. However, the role of major hormones that are closely related to secondary metabolism pathways in P. ginseng is poorly understood. To gain insight into their potential correlation, we performed a spatial synthesis analysis and studied the distribution of endogenous phytohormones and ginsenosides in different tissue regions of the entire P. ginseng plant. Gibberellins are growth hormones that accumulate in the fiber root. In contrast, abscisic acid (ABA), salicylic acid (SA), and jasmonic acid (JA), which are considered stress hormones, were predominantly found in the leaf and leaf peduncle. We observed a tissue-specific distribution of phytohormones consistent with the expression of genes involved in hormone biosynthesis that influenced ginsenoside synthesis and distribution. The aim of this study was to investigate the role of different endogenous phytohormones on triterpene metabolites in ginseng innate immunity.