Why is depression more common among women than among men?

Why is depression more common among women than among men?
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DOI:
10.1016/s2215-0366(16)30263-2
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发表时间:
2017-02-01
期刊:
影响因子:
64.3
通讯作者:
Kuehner, Christine
Kuehner, Christine
中科院分区:
医学1区
文献类型:
--
作者:
Kuehner, Christine

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女性在一生中患抑郁症的可能性是男性的两倍。本系列论文总结了有关抑郁症患病率、发病率和病程性别差异的流行病学证据,以及可能解释性别差异的因素。与性别相关的抑郁症亚型被认为是存在的,其中发展亚型具有最强的潜力,有助于性别差距。有限的证据表明风险因素与抑郁症有具体联系。未来的研究可以从一个transdiagnosis的角度,允许从那些预测一般的精神病理学的内在和跨内化和外化频谱的具体易感性的分化。研究领域标准框架的整合将允许在发展转型和环境设置的背景下检查核心心理功能的性别差异。监测导致性别差距的因素中不断变化的社会经济和文化趋势,以及这些趋势对男性和女性精神病理学症状表达变化的影响将非常重要。
Women are about twice as likely as are men to develop depression during their lifetime. This Series paper summarises evidence regarding the epidemiology on gender differences in prevalence, incidence, and course of depression, and factors possibly explaining the gender gap. Gender-related subtypes of depression are suggested to exist, of which the developmental subtype has the strongest potential to contribute to the gender gap. Limited evidence exists for risk factors to be specifically linked to depression. Future research could profit from a transdiagnostic perspective, permitting the differentiation of specific susceptibilities from those predicting general psychopathologies within and across the internalising and externalising spectra. An integration of the Research Domain Criteria framework will allow examination of gender differences in core psychological functions, within the context of developmental transitions and environmental settings. Monitoring of changing socioeconomic and cultural trends in factors contributing to the gender gap will be important, as well as the influence of these trends on changes in symptom expression across psychopathologies in men and women.