Correction for head movements in positron emission tomography using an optical motion-tracking system
Correction for head movements in positron emission tomography using an optical motion-tracking system
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DOI：
10.1109/tns.2002.998691
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发表时间：
2002-02-01
影响因子：
1.8
通讯作者：
Fulham, MJ
中科院分区：
文献类型：
--
作者：
Fulton, RR;Meikle, SR;Fulham, MJ
能够在所有六个自由度中校正头部运动的方法已经被提出用于正电子发射断层扫描（PET）脑成像，但尚未在人类研究中得到证实。这些方法依赖于头部运动相对于重建坐标系的精确测量。我们提出了直接校准的光学运动跟踪系统的重建坐标系使用成对的坐标测量同时从PET扫描仪和跟踪系统。我们还描述了运动校正的实现，基于最初由Picard和Thompson描述的多采集帧方法，使用由运动跟踪系统提供的数据。在霍夫曼脑模型和正常志愿者的动态PET扫描中证明了对多个六自由度运动的有效补偿。我们的结论是，减少失真和提高定量准确性，可以实现这种方法在PET脑研究退化的头部运动。
Methods capable of correcting for head motion in all six degrees of freedom have been proposed for positron emission tomography (PET) brain imaging but not yet demonstrated in human studies. These methods rely on the accurate measurement of head motion in relation to the reconstruction coordinate frame. We present methodology for the direct calibration of an optical motion-tracking system to the reconstruction coordinate frame using paired coordinate measurements obtained simultaneously from a PET scanner and tracking system. We also describe the implementation of motion correction, based on the multiple acquisition frame method originally described by Picard and Thompson, using data provided by the motion tracking system. Effective compensation for multiple six-degree-of-freedom movements is demonstrated in dynamic PET scans of the Hoffman brain phantom and a normal volunteer. We conclude that reduced distortion and improved quantitative accuracy can be achieved with this method in PET brain studies degraded by head movements.